Abamune is an anti-HIV drug that reduces the amount of virus in the body. Anti-HIV drugs such as Abamune slow down or prevent damage to the immune system and reduce the risk of developing AIDS-related illnesses. Abamune belongs to a class of drugs known as nucleoside reverse transcriptase inhibitors (NRTIs). When HIV infects a cell, the enzyme reverse transcriptase copies the viral single-stranded RNA genome into double-stranded viral DNA. This viral DNA is then integrated into the CD4 chromosomal DNA and can go on to reproduce in the body. Four natural nucleosides complete the DNA synthesis: adenosine, cytidine, guanosine, and thymidine. An NRTI drug substitutes a defective version of one of the nucleosides, causing premature termination of the proviral DNA chain. In July 1999, Abamune was approved by the European Union licensing body for use in combination with other anti-HIV drugs. The drug was licensed in the United States in December 1998. Once-daily Abamune was also approved in the European Union in November 2004.
Other names for this medication:
Abacavir,
Abalam,
Epzicom,
Kivexa,
Abamune,
Virol,
Ziagen,
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