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After noting that methotrexate exposure induces prolonged elevations of the glutamate analog homocysteic acid (HCA) within cerebrospinal fluid, we tested whether intrathecal injection of HCA would produce memory deficits similar to those observed after intrathecal methotrexate. Effectiveness of bovine gallstone (Goou) and bear gall powder (Yutan) on chronic liver diseases: a preliminary report. After the framework and tool were subjected to face-validity critique among PFQ investigators, the concept of synergy was added.

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To investigate emergent literacy skills, including phonological awareness when presented with an initial phoneme-matching task and letter knowledge when presented with a letter-naming task in Thai preschoolers, and to identify key factors associated with those skills. Effects of two truncated forms of human calcitonin-gene related peptide: implications for receptor classification. Platelets and microparticles (MPs) are important for hemostasis and thrombosis, however their participation during AF is not well known.

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The bisphosphonate 2-PEBP inhibits cyclosporin A induced high-turnover osteopenia in the rat. AlkB homologues in thermophilic bacteria of the genus Geobacillus HMGA2: a biomarker significantly overexpressed in high-grade ovarian serous carcinoma. Furthermore, micro-Raman results indicate that the a-Si has been crystallized into nanocrystalline Si.

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Raccoon polyomavirus 1 (RacPyV1) is the suspected cause of an outbreak of fatal brain tumors among raccoons (Procyon lotor) in the western United States. We explored the theoretical underpinnings of a commonly used training strategy by examining issues of training and transfer of skill in the context of a complex video game (Space Fortress, Donchin, 1989). With its unique dose-distribution properties, proton therapy has the potential to improve the therapeutic ratio of prostate radiation by allowing for an increase in dose without a substantial increase in side effects.

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Just as physically retracting a sessile drop reduces its contact angle with a surface, it was speculated that dissolution could cause contact angles to be reduced. Siderophore biosynthesis a substrate specificity assay for nonribosomal peptide synthetase-independent siderophore synthetases involving trapping of acyl-adenylate intermediates with hydroxylamine. In a randomized, placebo-controlled, double-blind trial, 35 patients with early scleroderma received subcutaneous injections of either IFNalpha (13.5 x 10(6) units per week in divided doses) or indistinguishable placebo. The findings suggest that in a cholera-endemic area, HIV infection is associated with an increased risk for cholera.

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Polycystic kidney disease prevented by transgenic RNA interference. We demonstrate that both relaxation and nondynamical correlation are important for accurately describing shape resonances. To investigate the immunobiology of Rpf domain from Micrococcus luteus. By examining the intracellular localization of green fluorescent protein (GFP) fusion proteins that bind to unique phosphoinositide species, we also demonstrate that phosphatidylinositol-4-phosphate (PI4P), the product of OCRL1, is present at the inclusion membrane.

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Maternal thyroid hormone trajectories during pregnancy and child behavioral problems. Findings support a lower diagnostic cut-off for adolescent BPD, to identify those at-risk at an early stage. Extensive differences in terms of sperm production such as testicular structure and organization, hormonal regulation are reported between humans and insects, yet it is not known to what extent components of the process could be conserved and furthermore to what extent the underlying genetic regulators could be shared from insects to mammals. Accurate experimental data increasingly allow the development of detailed elementary-step mechanisms for complex chemical and biochemical reaction systems. Our findings indicate the need for a careful assessment of (18)F-FDG uptake in patients treated with ARBs.

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We describe a novel design of an inverse ?erenkov accelerator for preinjected relativistic electrons. Male-to-Female Sex Reassignment Surgery Using the Combined Technique Leads to Increased Quality of Life in a Prospective Study. Elevated plasma cardiac troponin T (cTnT) levels in patients with neuromuscular disorders may erroneously lead to the diagnosis of acute myocardial infarction or myocardial injury. Digit span performance was significantly decreased in only the backward direction. Thirteen patients recovering from acute coronary syndrome were interviewed by telephone and seven nurse mentors completed a survey after completing the program.

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Inhibitory Effects of Antimicrobial Peptides on Lipopolysaccharide-Induced Inflammation. Three patients presenting to the West Roxbury VA Medical Center were identified as having a contractile, focal narrowing in the distal esophagus by upper GI series. Bark pockets included within the trunks of two Japanese cedar trees harvested near Murakami, dating between 1972 and 1982, exhibited lead isotope ratios indicative of Japanese-sourced lead. We apply our method on a time-series RNA-Seq data set of Escherichia coli as it transitions from growth to stationary phase over five hours and investigate the various activity in gene regulation process by taking advantage of the correlation between regulatory gene pairs to examine their activity on a dynamic network. Levels of pyridinoline and deoxypyridinoline in urine, and the level of alkaline phosphatase in serum from patients with bone metastatic prostate cancer were significantly greater than levels in patients with benign prostatic hyperplasia or localized prostate cancer.

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Our results suggest that MUC1 is related to malignant character but MUC5AC alone is related to benign character in IPMTs and that malignant potential of IPMTs expressing MUC2 depends on the degree of MUC2 expression. MnSOD genotype and prostate cancer risk as a function of NAT genotype and smoking status. The two mutants were able to stimulate cellular proliferation, albeit with reduced efficiency when compared with wild-type thioredoxin.(ABSTRACT TRUNCATED AT 250 WORDS)

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Aqueous N-heterocyclization of primary amines and hydrazines with dihalides: microwave-assisted syntheses of N-azacycloalkanes, isoindole, pyrazole, pyrazolidine, and phthalazine derivatives. In warm-blooded vertebrates, neuronal nicotinic acetylcholine receptors (nAChRs) are distinguished from muscle endplate receptors by their ligand affinities and sensitivity to several toxins.

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The aim of the study was to evaluate the incidence, baseline disease characteristics, and disease location based on the Paris classification in pediatric inflammatory bowel disease (IBD) in the Hungarian nationwide inception cohort. One of the most important issues in the development of gas sensors for breath analysis is the fabrication of gas sensor arrays that possess different responses for recognizing patterns for volatile organic compounds (VOCs). Multiple sleep latency test in patients with obstructive snoring Lipopolysaccharide (LPS) caused a concentration-dependent increase of released and cell-associated interleukin-1 (IL-1) in resident peritoneal macrophages from the mouse. This review will discuss the current knowledge of microtubule-based motor proteins (including kinesins and hypothetical dyneins) and will make some hypothesis about their role in the pollen tube.

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The total anthocyanin content was 1.9 g per 100 g dried fruits on cyanidin 3-glucoside basis. Exclusion of alternative exon 33 of CaV1.2 calcium channels in heart is proarrhythmogenic.

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The synthesis of crystalline two-dimensional polymers (2DPs) with proper bandgaps and well-defined repeating units presents a great challenge to synthetic chemists. Since ET is linked to increased risk for cognitive impairment, and such impairment may not be accurately perceived, cognitive functioning should be proactively and regularly screened in ET. Analyses of data from the Add Health revealed that IQ was related to mortality risk, such that respondents with relatively lower IQs were significantly more likely to experience early life mortality when compared to respondents with relatively higher IQs. We show that approaches such as ultrasound waves, laser, and microneedle patches have successfully been employed to physically disrupt the stratum corneum structure for enhanced transdermal delivery.

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When Streptococcus bovis JB1 was repeatedly transferred in a medium that contained the non-metabolizable glucose analog, 2-deoxyglucose, it lost its phosphotransferase system (PTS) for glucose but was still able to take up glucose via a facilitated diffusion mechanism. Estimating free-energy barrier heights for an ultrafast folding protein from calorimetric and kinetic data. A case of Sturge-Weber syndrome (SWS) with gastrointestinal hemorrhage is presented. Little is known about patient characteristics as predictors for outcome in manualized short term psychodynamic psychotherapy (PDT).