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Our results indicate that the Nrf2-ARE pathway is important to maintain resistance to irradiation, but that it operates as a second-tier antioxidant adaptive response system activated by radiation only under specific circumstances, including those that may be highly relevant to tumor response during standard clinical dose-fractionated radiation therapy. Active range of motion, from pre- to postintervention, increased by 35 degrees in the shoulder, 65 degrees in the wrist, and 70 degrees in the thumb. Expression of the calcium binding proteins Necab-1,-2 and -3 in the adult mouse hippocampus and dentate gyrus.

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The surgical outcome and long-term follow-up were retrospectively analyzed. Appraising MicroRNA-155 as a Noninvasive Diagnostic Biomarker for Cancer Detection: A Meta-Analysis. Each formulation treats different aspects of the relevant phenomena, including the thresholdlike behavior and the role of coherence of individual spikes.

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With symmetrical omni-directional settings (Omni/Omni), performance was poorer than a control group of 14 listeners with normal hearing tested unaided: Aided listeners required 4.3 dB more favorable SNR for criterion performance. Bovine tuberculosis is a zoonotic disease of global public health concern. A cross-sectional study was performed in 37 hospitals and mother-child clinics from different health sectors in Jordan. The spectral shifts of 1733 cm(-1), 1604 cm(-1) and 1236 cm(-1) and different spectra between the moist and dry spectra indicated that carbonyl CO and CO groups preferred to combine with water molecules to form hydrogen bonds. Accurate assessment of collateralization extent has become an important goal because of the discovery of agents that stimulate the growth of coronary collateral vessels.

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Management of stage T1 tumors of the bladder: International Consensus Panel. The recombinant plasmid pET-15b-cdtB was successfully constructed and the recombinant CdtB protein which has the DNaseI-like activity was obtained.

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As the role of dothistromin in the disease is unknown the expression of dothistromin genes was studied to reveal clues to its function. Stress and the epigenetic landscape: a link to the pathobiology of human diseases? We have shown before that arginine at mild pH can effectively dissociate protein-protein or protein-ligand interactions, e.g. Occult odontoid fractures without preceding trauma are rarely reported in the literature and may be difficult to diagnose. Comparison of the quantitative performance of a Q-Exactive high-resolution mass spectrometer with that of a triple quadrupole tandem mass spectrometer for the analysis of illicit drugs in wastewater.

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Statistical analysis of data from multicenter, randomized, controlled trials. We previously found that mice over-expressing the human APPwt transgene, a gene triplicated in Ts65Dn but not Ts1Cje, also show increased wake and theta power during sleep. The findings are consistent with recent addiction models suggesting that chronic cocaine-related neuroadaptations affects learning and memory function, which in turn, influences drug use outcomes. Thiazolidinediones are insulin sensitizing drugs that target the peroxisome proliferator-activated receptor (PPAR) gamma.

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Here, we show how a comprehensive quantitative description of conformational space and dynamics of a single lipid molecule can be achieved via the principal component analysis (PCA). A systematic search of original research was conducted using MEDLINE, PUBMED and Google Scholar databases. Because of the wide spread of magnetic resonance image (MRI), it may be increasing to find a dissecting aneurysm (DA) of the posterior inferior cerebellar artery (PICA) that causes headache without associated hemorrhage or infarction. We searched for psychiatric surveys that were based on interviews of unselected refugee populations and that included current diagnoses of post-traumatic stress disorder, major depression, psychotic illnesses, or generalised anxiety disorder. Our results showed that plates with locked screws provided greater stability during cyclic loading than the plate without locked screws.

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Collection of the eggs using experimental animal models is needed for a sustainable supply. We show that the hTf transgene was expressed only from 5 days postpartum onward. Spatiotemporal Variability of Methane Emissions at Oil and Natural Gas Operations in the Eagle Ford Basin. She was kept on a ventilator for the first 6 days of life, and had an uneventful Neonatal Intensive care stay until her 47th day of life when she developed sepsis that required ventilator support for 3 days.

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chinensis and Lonicera similis (cultivars) were used to make the chromosomal preparation. However, when the effects of aggregation and recall period are combined, it is difficult to predict which of the two has the greater influence. Enhanced knee flexion during pre-swing phase also aided flexion during swing, especially when response to stimulation was compromised.

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Saccharomyces cerevisiae membrane sterol modifications in response to growth in the presence of ethanol. Certain pathogens commonly found in the canine oral flora may cause severe secondary infections, which may result in sepsis and even death. Combination treatment was associated with a strong accumulation of double-stranded DNA breaks, G2/M arrest, and apoptotic cell death. Both arginine and fructose stimulate pH-independent resistance in the wine bacteria Oenococcus oeni. Finally, NCCLS proposed the document for Reference Interval, how to determine, utilize the reference interval in clinical laboratory, in 1992.

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Role of FTO in Adipocyte Development and Function: Recent Insights. Effect of flux creep on the temperature dependence of the current density in Y-Ba-Cu-O crystals.

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Assay of free ferulic acid and total ferulic acid for quality assessment of Angelica sinensis. Systolic dysfunction and diastolic dysfunction are common in patients with normal coronary arteries who have hypertension, diabetes, and/or obesity. We present a successful second attempt at left anterior descending artery CTO PCI with no interventional collaterals. Synthesis and characterization of water-soluble two-photon excited blue fluorescent chromophores for bioimaging.

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Ten markers were placed on a synthetic mandible, and landmark coordinates and linear and angular measurements were determined with the CMM. A national stratified probability sample of 1,519 women and 1,475 men aged 20-64 years in urban China completed a computer-administered survey in 1999-2000.

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To describe the natural history of vitamin D deficiency in an at-risk population of African migrants living in Sydney. An overweight woman, aged 58 years, presented for follow up of hypertension, diabetes and dyslipidaemia. Results are expected to be helpful in assessing physical fitness and evaluating physical activity in older adults. The high abundance of parasitism in the fossil record of insects can reveal important aspects of parasitic lifestyles in various evolutionary lineages.

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Diagnostic, clinical and histopathological problems in congenital atresia of the biliary tract Adult male Syrian hamsters were killed at nine intervals during a 24 hr period in the autumn, after 2 months either indoors in controlled conditions or in natural outdoor conditions.

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Laparoscopic gastrectomy was performed entirely laparoscopically with intracorporeal anastomosis, followed by specimen retrieval via a suprapubic incision. We performed a systematic review and meta-analysis of data from experiments testing the efficacy of antidepressants versus no treatment to reduce infarct volume or improve neurobehavioral or neurogenesis outcomes in animal models of stroke. We present a case of Plasmodium vivax infection in a soldier, 4 months after returning from Afghanistan.

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The regulation of malaria parasitaemia: parameter estimates for a population model. In the presence or absence of atherosclerosis, young adults can experience a myocardial infarction. No influence of diabetes nor of diabetic retinopathy was observed on the concentrations of plasmalogen-type phospholipids. Some aspects of respiration and respiration inhibitors in low temperature effects of the cotton plant.

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We report a quantitative evaluation of the clinical accuracy of a MRI-guided robotic prostate biopsy system that has been in use for over five years at the U.S. The aim of this study was to conduct the first national study of Australian NP prescribing practices. The cleavage of caspase 7 and poly ADP-ribose polymerase induced by local anesthetics were effectively blocked by caspase inhibitors. To identify valid and reproducible methods for quantifying anatomic outcome measures for eyes with choroideremia (CHM) in clinical trials. KRAS mutational analysis is the standard of care prior to initiation of treatments targeting the epidermal growth factor receptor (EGFR) in patients with metastatic colorectal cancer.

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We carried out a national survey on childhood febrile illnesses in order to collect useful information for the differential diagnosis. The study serves as a biomechanical basis for novel artificial prostheses and for clinical hip joint replacements. To compare the postoperative results of phacotrabeculectomy with implantation of PMMA, foldable silicone or foldable hydrofobic acrylic intraocular lens (IOL). Colorectal resections alter colonic motility, including disruption of control by neural or bioelectrical cell networks.

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In in vivo studies, the disposition of MRK16 was determined in tumor-bearing mice after intravenous administration. The authors therefore recommend this approach in selected cases only. Studies addressing acute intervention and outcome in the therapy of vertebrobasilar thrombosis were reviewed.

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This paper outlines a method by which the concentration of each of the toxic components, determined by high-resolution congener-specific gas chromatographic analysis, may be converted to equivalent toxic concentrations of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Beauty parlor stroke revisited: An 11-year single-center consecutive series. One of the key acceptance criteria is coating retention to the physical stresses experienced during implantation. Interhemispheric transfer was examined in 13 normal controls and in 13 children with hydrocephalus and partial agenesis of the corpus callosum involving a missing splenium associated with spina bifida meningomyelocele and aqueductal stenosis. We recruited 97 patients with primary glomerulonephritis and measured 24-h urinary protein excretion, 24-h urinary albumin excretion, selectivity index, albumin:creatinine ratio, urinary IgG:creatinine ratio, fractional excretion of albumin (FE Alb) and fractional excretion of IgG (FE IgG) at baseline.

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Contributions of sodium and chloride to NaCl-induced hypertension. Epidemiological and genetic studies indicate that ethnic/genetic background plays an important role in susceptibility to primary open angle glaucoma (POAG).

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Effect of osteogenic induction on the in vitro differentiation of human embryonic stem cells cocultured with periodontal ligament fibroblasts. The interaction between the arginine glycine and aspartic acid motif (RGD) of integrin ligands such as vitronectin and the integrin receptor alphaVbeta3 in mediating cell attachment has been well described. This study also assessed the correlations between radiologic and clinical findings.

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The aim of the study was to prospectively assess the incidence, the preventability, and the factors contributing to adverse events (AEs) in surgical departments of Tunisian hospitals. Phase zero trials: a novel approach in drug development process. This study tests this specificity-hypothesis and extends previous research by conceptualizing motivation to include both reactivity to reward and punishment. Our findings suggest potential usefulness of combining UCN-01 in topoisomerase I inhibitor-based drug therapy for the treatment of breast cancer with a dysfunctional p53 gene. SUMMARY: The aim of this study was to estimate the incidence of hip fracture in Kermanshah, Iran.

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Genes regulated by caloric restriction have unique roles within transcriptional networks. Stapled pulmonary tractotomy: a rapid way to control hemorrhage in penetrating pulmonary injuries. These results imply the potentially clinical application of PNS to overcome the negative side effects of doxorubicin. These results indicate that ecto-ErbB4 could be used in vivo as a tool to manipulate the neuregulin1/ErbB system. The soft tissue phantom was designed based on a three-dimensional clustered lumpy background with included low-contrast lesions (spherical and anthropomorphic).

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Also discussed are whether non-AUG initiation plays any role in translational control and whether start codon accuracy is regulated in eukaryotes. The differential expressions of HSP70 in breast cancer drug sensitive cell line MCF7 and MDR cell line MCF7/ADR affect the cytotoxic activity of immunologic effector cells. Estimating the effectiveness of cardiac biomarkers involves identifying how they help to improve health and how we can measure this improvement. Humans possess a medium-sized Tas2r repertoire encoding three broadly and several narrowly tuned receptors plus receptors with intermediate tuning properties. Confidence in results must be rigorously evaluated for the sources of variability in all of the bottom-up and top-down elements.

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SIMPLE is a superheated droplet detector (SDD) experiment designed to search for the evidence of spin-dependent weakly interacting neutralino dark matter (WIMPs). The qRT-PCR analysis revealed that the expression of VvSUC27 was 1,000 times higher than that of the autologous tobacco sucrose transporter, which suggested that the markedly increased growth rate of transformants was because of the heterogeneously expressed gene. Five cytokines (IL-10, IL-17, CCL2, CXCL10, and G-CSF) were higher while 3 were lower in the patient than in controls (IL-2, IL-8, and CCL11). A multimethod investigation of the behavioral activation system in bipolar disorder. Comparative study of knowledge, attitude and practices among antenatal care facilities utilizing and non-utilizing women.

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Some studies have hypothesized that filaggrin gene mutations (FLG) may also play a role in AA, particularly in patients with comorbid atopic disease. A modified ABCDE model of flowering in orchids based on gene expression profiling studies of the moth orchid Phalaenopsis aphrodite. Perceptual filling in is facilitated at the corresponding area of retinal scotomas.