Difluzol is an antifungal medication used in the treatment of several fungal infections. The drug is used orally and intravenously. Difluzol widely distributes into body tissues, nails and fluids including saliva, sputum, vaginal secretions. Difluzol does not undergo first pass metabolism and is excreted mostly in the urine and some in the feces. This drug can also be used in the pediatric population. Difluzol works by altering the fungal cell membrane. It exerts its fungistatic effect by selectively inhibiting 14-alpha demethylase. This is a cytochrome P-450 enzyme that is necessary for synthesizing ergosterol, which is an important component of the fungal cell membrane. 14-alpha demethylase converts lanosterol to ergosterol. Without ergosterol, 14 alpha-methyl sterols increase which subsequently causes the fungal cell membrane to exhibit increased cellular permeability. This causes the components inside the cell to leak.
Other names for this medication:
Fluconazole,
Diflucan,
Afumix,
Afungil,
Batacan,
Candidin,
Diflazon,
Difluzol,
Difluzole,
Dizole,
Dofil,
Duracan,
Efac,
Elazor,
Exomax,
Farzul,
Fluc,
Flucomed,
Flucon,
Fluconapen,
Fluconazol,
Flusenil,
Flutec,
Fluvin,
Fluzol,
Fluzole,
Fluzone,
Forcan,
Govazol,
Honguil,
Ibarin,
Kifluzol,
Lavisa,
Logican,
Lucon,
Medoflucon,
Novacan,
Omastin,
Ozole,
Ponaris,
Rifagen,
Sacona,
Stabilanol,
Syscan,
Ticamet,
Trican,
Triflucan,
Trizol,
Uzol,
Varmec,
Zemyc,
Zolax,
Zoldicam,
Zolen,
Zoloder,
Zucon,
Similar Products:
Overal,
Topcillin,
Vertisal,
Cicloviral,
Kofron,
Ketiapin,
Hydroxyzine,
Seclo,
Pumpitor,
Gastrium,
Telviran,
Diflucan,
Hycid,
Calutol,
Ketazol,
Pantocid,
Doxin,
Nodiril,
Levocine,
Vilerm,
Amineurin,
Paxyl,
Sebrane,
Trupan,
Antabuse,
Venla,
Mediklin,
Clopicard,
Vivorax,
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