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Efac (Fluconazole)

Efac is a triazole medicine used to treat fungal infections. It is effective against a broad spectrum of fungi including: Dermatophytes (tinea infections); Yeasts such as candida and malassezia; Systemic infections such as cryptococcosis and coccidioidomycosis. In New Zealand, Efac is available as 50 mg, 150 mg and 200 mg capsules on prescription (Efac). There is also a 2 mg/ml injection for intravenous use. In New Zealand, the Pharmaceutical Schedule subsidy of the capsules requires Specialist recommendation except for single-dose use, which is on general prescription and also available over the counter. Efac binds to the fungal p450 enzymes and stops the cells making ergosterol, the main component of the cell wall. Efac is well absorbed orally with or without food. It is widely distributed in body tissues. It takes 22 to 30 hours for half of the medication to be cleared from the bloodstream and may take several days of continuous treatment to reach a steady concentration. The drug is eliminated unchanged in the urine so doses should be reduced if there is kidney disease.

Other names for this medication:
Fluconazole, Diflucan, Afumix, Afungil, Batacan, Candidin, Diflazon, Difluzol, Difluzole, Dizole, Dofil, Duracan, Efac, Elazor, Exomax, Farzul, Fluc, Flucomed, Flucon, Fluconapen, Fluconazol, Flusenil, Flutec, Fluvin, Fluzol, Fluzole, Fluzone, Forcan, Govazol, Honguil, Ibarin, Kifluzol, Lavisa, Logican, Lucon, Medoflucon, Novacan, Omastin, Ozole, Ponaris, Rifagen, Sacona, Stabilanol, Syscan, Ticamet, Trican, Triflucan, Trizol, Uzol, Varmec, Zemyc, Zolax, Zoldicam, Zolen, Zoloder, Zucon,

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Eosinophilic pustular folliculitis in infancy: report of two affected brothers. More in-depth research and analysis is needed to further explain this correlation of health care providers in the military, the amount of leave days they have accrued, and burnout.

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Their lipophilic character was shown to be sufficient for their direct use as coating antigens in microtiter plate assays. We have equated diagnosis of Asperger syndrome with ASD-level 1 of support. Layered inorganic materials, such as the transition metal dichalcogenides (TMDs), have attracted much attention due to their exceptional electronic and optical properties. Twenty-two people with PNES, with confirmed video EEG, were recruited by means of convenience sampling from two hospitals.

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They contain mRNAs and many proteins including numerous types of RNA-binding proteins, and have been studied in connection to major cellular events such as protein synthesis as well as disease. In this paper, we presented the isolation and characterization of maize Aux/IAA genes in whole-genome scale. A hypomorphic vasopressin allele prevents anxiety-related behavior. Comparisons were made between methods in terms of accuracy of individual measurements as well as evaluation of treatment outcomes.

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Stress and serial adult metamorphosis: multiple roles for the stress axis in socially regulated sex change. Phaeobacter inhibens DSM 17395, a model organism for marine Roseobacter group, was studied for its response to its own antimicrobial compound tropodithietic acid (TDA). An 89-year-old woman with a history of traumatic injury was referred to our hospital for further evaluation of anemia.

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Developing categorical diagnoses that have biological meaning within the clinical phenotype of psychosis (schizophrenia, schizoaffective disorder, and bipolar I disorder with psychosis) is as important for developing targeted treatments as for nosological goals. Lower incidence of vascular events following small artery ischemic stroke. Serotonin metabolism in rat brain after surgical diversion of the portal venous circulation. In silico modeling and in vivo efficacy of cancer-preventive vaccinations.

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They have an important role in providing care globally in response to physician shortages. Feasibility of a self-help web-based intervention targeting young cancer patients with sexual problems and fertility distress. N-Radical-Initiated Cyclization through Insertion of Sulfur Dioxide under Photoinduced Catalyst-Free Conditions.

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Sharpened VO2 Phase Transition via Controlled Release of Epitaxial Strain. NT-pro-BNP during hypoglycemia and hypoxemia in normal subjects: impact of renin-angiotensin system activity.

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Patients with primary central nervous system lymphoma (PCNSL), primitive neuroectodermal tumor (PNET), germ cell tumor, cancer metastasis to the brain, or low or high grade glioma were eligible. This was a prospective, open-label, single-dose, parallel-group study. Research in animals and humans has shown that mastication maintains cognitive function in the hippocampus, a brain area important for learning and memory. Therefore, the aim was to pharmacologically characterize the novel small-molecule antagonist PF-05190457 and assess translational pharmacology ex vivo. Expired antivenom: good efficacy in a severely envenomed cat bitten by Sistrurus miliarius miliarius (Carolina Pigmy Rattlesnake).

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Endoscopic Ultrasonography-Guided Fine Needle Aspiration Can Be Used to Rule Out Malignancy in Autoimmune Pancreatitis Patients. A single dose of antidepressant alters eye-gaze patterns across face stimuli in healthy women. Bovine blastocyst development rate in vitro is influenced by selection of oocytes by brillant cresyl blue staining before IVM as indicator for glucose-6-phosphate dehydrogenase activity. What endocardial right ventricular pacing site shows better contractility and synchrony in children and adolescents?

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MDR is usually characterized by overexpression of ABC (ATP-binding cassette) protein transporters such as P-gp, MRP1, and ABCG2. The complete assignment of the product ions obtained upon fragmentation of oxidized glutathione in an ion trap is presented. Posterolateral rotatory instability of the elbow: a case report and literature review.

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Mediation analysis of the association between use of NRT for smoking reduction and attempts to stop smoking. Contrast-enhanced lumbar magnetic resonance image showed multiple intradural and extramedullary masses and cysts from T12 to S1. Effects of a rice major gene Ur1 (Undulate rachis -1) on panicle and grain traits. For the intravital fluorescence microscopy measurements, the patella tendon was partially resected for visualization of the intraarticular synovial tissue of the knee joint. Green synthesis, characterization and anti-inflammatory activity of silver nanoparticles using European black elderberry fruits extract.

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Moreover, deletion of the N-terminal 46-amino acid presequence results in a cytosolic localization of the epitope-tagged protein. It appears that the presence of pericardium in the composite grafts may have inhibited this property. A protocol for quantifying lipid peroxidation in cellular systems by F2-isoprostane analysis.

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iTRAQ combined with the LC-MS/MS technique can effectively screen differential proteins in placenta tissues of patients with pre-eclampsia. Using a full-length VEGF promoter-luciferase construct, we found that CsA markedly induced VEGF transcriptional activation through the protein kinase C (PKC) signaling pathway, specifically involving PKC zeta and PKC delta isoforms.

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Trends in overweight and obese adults in Malaysia (1996-2009): a systematic review. Clinical response was evaluated following WHO criteria and classified as complete response (CR), partial response (PR), stable disease (StD) and progressive disease (PD). These studies show, for the first time, that mild systemic hyperthermia can prevent the generation of T1D in a clinically relevant mouse model.

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Visualization of interaction between ribosome-inactivating proteins and supercoiled DNA with an atomic force microscope. These data highlight the conserved role of NF-kappaB during fibrogenesis. A thermodynamic analysis of steady state absorption and fluorescence spectra demonstrates that all chlorophylls are energetically coupled, while the kinetics of chlorophyll photooxidation indicate that triplet chlorophyll-carotenoid coupling is also conserved during pigment binding in vitro. This effect was evident by 6 h after exposure to two cigarettes. Involvement of cytosolic phospholipase A2 and secretory phospholipase A2 in arachidonic acid release from human neutrophils.

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