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Penile erection is caused by the engorgement of the penis with blood. This engorgement occurs when the blood vessels delivering blood to the penis increase the delivery of blood and the blood vessels carrying blood away from the penis decrease the removal of blood. Under normal conditions, sexual stimulation leads to the production and release of nitric oxide in the penis. Nitric oxide then activates the enzyme, guanylate cyclase, which causes the production of cyclic guanosine monophosphate (cGMP). It is the cGMP that is primarily responsible for the erection by affecting the amount of blood that the blood vessels deliver and remove from the penis. Intagra inhibits an enzyme called phosphodiesterase-5 (PDE5) which destroys the cGMP. Thus, Intagra prevents the destruction of cGMP and allows cGMP to accumulate and persist longer. The longer cGMP persists, the more prolonged the engorgement of the penis. The FDA approved Intagra in March 1998.

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The proposed higher order designs have similar inter sensor spacings as traditional first and second order differential arrays. Different requirements for action potentials in the induction of different forms of long-term potentiation. Likewise, distinct substrates for CK2 are noted in the transcriptionally active compared with inactive nucleosomes. Endoscopic closure by using through-the-scope endoclips was attempted in all cases of intraprocedural perforations immediately after perforation was recognized during the procedure.

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Transdermal nicotine administration and the electroencephalographic activity of substance abusers in treatment. Between 1982 and 1986, 27 infants with severe BPD had at least two echocardiographic studies. High-resolution 19F NMR spectroscopy at 9.4 T was used to study the difference in the metabolite pattern of 5-fluorouracil (5-FU) between viable and necrotic tissues of C38 murine colon tumors grown in C57BI/6 mice. Ethnicity does not affect the homocysteine-lowering effect of B-vitamin therapy in Singaporean stroke patients.

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Effects of halothane on calcium release from sarcoplasmic reticulum of rabbit psoas and semitendinosus skinned muscle fibers. These case present an evident example of a genotype-phenotype correlation in glycogen storage disease type II. Effects of linking 15-zinc finger domains on DNA binding specificity and multiple DNA binding modes. difficile infections (CDIs) in a cohort of HIV-infected individuals. Film made of kafirin alone had antimicrobial activity against Listeria monocytogenes, however, films incorporating citral exhibited the highest antimicrobial activity against hydroxyurea renal dosing for augmentin Campylobacter jejuni, L.

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Necrotizing fasciitis resulting in fatal lung aspergillosis: Uncommon pathogenesis. This study was designed to investigate the activation type of splenic macrophages in cirrhotic patients with tetracycline repressor protein sequences hypersplenism and HBV infection to assess the immune function of splenic macrophages. V-set and transmembrane domain-containing protein 5 (Vstm5), a newly characterized small membrane glycoprotein, can induce membrane protrusions in various cells. Randomised controlled trials of TRT versus no treatment, or other forms of treatment, in adult patients with tinnitus.

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