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Kivexa (Abacavir)

Kivexa is a drug used as part of antiretroviral therapy (ART). It is manufactured by ViiV Healthcare. The FDA approved Kivexa late in 1998. Generic versions have been approved under PEPFAR. Kivexa is a type of drug called a nucleoside analog reverse transcriptase inhibitor, or nuke. These drugs block the reverse transcriptase enzyme. This enzyme changes HIV’s genetic material (RNA) into the form of DNA. This has to occur before HIV’s genetic code gets inserted into an infected cell’s own genetic codes.

Other names for this medication:
Abacavir, Abalam, Epzicom, Kivexa, Abamune, Virol, Ziagen,

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Associated with substantial morbidity and mortality, these infections represent serious and sometimes catastrophic complications in the course of hospitalization of a preterm infant in the neonatal intensive care unit. In this study, we demonstrate that promoters for 10 predicted T3S transcriptional units are each transcribed in vitro by the major form of chlamydial RNA polymerase but not by an alternative form of RNA polymerase containing sigma(28). The aftermath of the impacts of periodic comet Shoemaker-Levy 9 on Jupiter was studied with the Wide Field Planetary Camera 2 on the Hubble Space Telescope. The aim of this study was to identify the factors predicting successful endoscopic treatment of EGC with signet ring cell histology.

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The regional and national genetic services programs should be strengthened and appropriate training programs should be developed in Schools of Public Health to provide the expertise and leadership that will be needed to guide the future of genetics in public health. Monovalent CCK(2) antagonist 2 did not stimulate receptor internalization. There has been little research into the effect of deprivation on the uptake of NHS Direct, a national nurse-led health helpline. The spinal cord is a glucocorticoid-responsive tissue, as demonstrated by hormonal effects on enzyme induction and by the presence of type II and type I glucocorticoid receptors in cytoplasmic extracts of this CNS region.

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With RIXS one nowadays probes a broad range of electronic systems reaching from simple molecules to complex materials displaying phenomena like peculiar magnetism, two-dimensional electron gases, superconductivity, photovoltaic energy conversion and heterogeneous catalysis. Majority of the bile duct stones (BDS) are radiolucent (RL) and are amenable to conventional endoscopic extraction techniques.

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The qualitative state of a system is represented by the marking of the net. The distributions of many Rorschach factors are markedly non-normal, and in some cases the shapes of the distribution for a particular factor may be different among different populations. DNA methyltransferase loading, but not de novo methylation, is an oocyte-autonomous process stimulated by SCF signalling.

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Colonic fermentation: a neglected topic in human physiology education. Increased SERPINB5 mRNA expression was correlated to increased metastasis and mRNA expression was regulated by methylation.

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The required CSA components are delivered by simultaneous numerical analysis of a few regular MAS spectra acquired under different spinning rates. Effects of disorder on the Raman spectra of GaAs/AlAs superlattices. This study focused on the incidence and characteristics of nonpancreatic neoplasms in IPMT patients. Unenhanced helical CT was performed with both a standard dose (260 mAs, pitch 1.5) and a low dose (50 mAs, pitch 1.5) in 121 patients suspected of having acute renal colic.

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Intrahepatic murine CD8 T-cell activation associates with a distinct phenotype leading to Bim-dependent death. Synthesis of 1,4-amino alcohols by Grignard reagent addition to THF and N-tosyliminobenzyliodinane. Oral cephalosporins had been, for years, a small group of compounds belonging to the first or second-generation cephalosporins, with a limited antimicrobial spectrum. In its 2015 annual conference, held on 4-6 September in Paris, France, the most recent progresses in the basic biology, management and treatment of liver cancer have been presented. Characterization and cytokine-stimulating activities of acidic heteroglycans from Tremella fuciformis.

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The latter was combined with the constant number MC method, to improve both speed and accuracy of the simulation. Lean and Six Sigma are improvement methodologies developed in the manufacturing industry and have been applied to healthcare settings since the 1990 s. In addition, with ULS labeling it is possible to label degraded DNA, a situation in which enzymatic labeling is known to perform unsatisfactorily. Medical records, radiographs, and computed tomography and magnetic resonance imaging scans were examined, and the presence of SCI was evaluated. A strategic approach of variable flap selections based on different tongue defects may achieve predictably better functional and aesthetic outcomes.

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We place particular emphasis on the translational value of animal studies and the relevance of TBI biomarkers. Modification of radiation response and teratogenic action by dimethyl sulphoxide in chick embryos. Induced pluripotent stem cells (iPSCs) are regarded as an alternative cell source in regenerative medicine. The early period after initiation of LVAD support of the failing human heart is associated with a relatively high incidence of significant ventricular arrhythmias after LVAD placement.

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From April 2007 through March 2012, a cohort of 317 consecutive patients undergoing surgery for gynecologic malignancies was evaluated in the retrospective study. The spread and metastases of ATL as well as other tumors has been associated with matrix metalloproteinases, especially the gelatinases MMP-2 and MMP-9. IBD patients with CDAD and discernable pseudomembranes more commonly present with fever, but their clinical outcome is similar to patients without pseudomembranes. The quality of some of the human plasma derived drugs such as coagulation factor VIII and coagulation factor IX which can be used for the treatment of hemophilia A and B, depends on their activity which may be affected by filtration.

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Quantitative real-time RT-PCR analysis results confirmed that cathepsin B and H genes expressed ubiquitously in all tested healthy tissues from miiuy croaker. Intraductal papillary mucinous neoplasm involving pancreaticobiliary maljunction and an aberrant pancreatic duct draining into the stomach: A case report and review of the literature. Although, there was no significant difference in the number of lymphatic vessels, the number of infiltrating CD11b-positive inflammatory cells was significantly reduced in the VEGF-C group, which suggested that VEGF-C upregulated the drainage of interstitial fluid and inflammatory cells via lymphatic vessels.

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Postoperative adverse events (AEs), prolonged length of stay (PLOS), and patient experience are common quality measures after thoracic surgical procedures. The sn-glycerol-3-phosphate O-acyltransferase of both potato and pea mitochondria used sn-glycerol-3-phosphate but not dihydroxyacetone phosphate as acyl acceptor and exclusively catalyzed the formation of 1-acyl-sn-glycerol-3-phosphate which subsequently served as substrate for the second acylation reaction at its C-2 position. Mastocytosis is a relatively common disorder characterized by mast cell collections in the skin and other organ systems.

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To compare the clinical presentation between chronic otitis media mucosal with squamous types. High expression level of T-box transcription factor 5 predicts unfavorable survival in stage I and II gastric adenocarcinoma. The resulting five monoclonal antibodies (mAbs HNEJ-1-5) recognized HNE-modified bovine serum albumin (BSA), but not native BSA in Western blot studies.

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It is questionable if little differences between the implant designs affect stress shielding and bone remodeling. Epidemiology of gastric cancer in the gangetic areas of west bengal. We conducted semen analyses using a computer-assisted sperm analyzer, measured the DEHP concentration by reversed-phase high-pressure liquid chromatography, and subjected the data to statistic processing by t-test and correlation analysis.

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Eating pathology among adolescent girls with attention-deficit/hyperactivity disorder. Structural adaptation with multiple intracellular changes is part of the remodeling process in hibernating myocardium. The distribution of versican and HA was examined by histochemical and immunohistochemical methods. Introduction of deletions and nucleotide exchanges resulted in an optimized DNA sequence but preservation of the IC50 in the low nanomolar range. Laparoscopic rectal cancer surgery with proper total mesorectal excision is a challenge for colorectal surgeons during trouble shooting.

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In fact, experiments with RNAi for the PGC1s show that the ability of ROS to induce a ROS scavenging programme depends entirely on the PGC1s. Single-incision and single-element array electrode to lower the defibrillation threshold. The Tidal Model focuses on providing support and services to people who need to live a constructive life. A diet low in sodium, high in potassium, and high in calcium is recommended to lower blood pressure. Although most studies report risk estimates that are in the same direction, there is significant heterogeneity in the size of the estimates.

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The most recent common ancestor of the Mormyroidea and Gymnotiformes was found to be a non-electrogenic basal teleost living more than 85 millions years earlier. Temperament was assessed with Temperament Assessment Battery for Children - Revised and Revised Dimensions of Temperament Survey batteries and EC with three subscales covering Cognitive ability, Motivation, and Maturity. The investigation on hybrid Co9 Se8 /rGO nanosheets as SIBs anode may shed light on designing new metal chalcogenide materials for high energy storage system. The role of antiinflammatory agents, decongestants, and combination products is reviewed. This approach to graduate education is congruent with recommendations of professional nursing organizations and responds to the educational needs of professional nurses and the health care needs of adult and elders.

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Since PGE2, NO and IL-1 beta have been implicated as modulators of steroidogenesis, experiments have been undertaken to determine how IL-1 beta-induced NO and PGE2 production may affect steroidogenesis in cultures of ovarian dispersates obtained from untreated adult oestrous rats and to compare the action of IL-1 beta in cultures of granulosa/luteal (GL) cell-only cultures and GL cells co-cultured with peritoneal macrophages. Inhibition of mitochondrial complex I may account for IDDM induced by intoxication with the rodenticide Vacor. In contrast, deletion of Rax in the eye generated an anophthalmic phenotype. New techniques to conduct these studies include RNA inhibition and development of transgenic animal models. These results suggest that the skewing to the Th2-type T cell response in atopic patients is a response not only to allergens, but also to bacterial antigens, compared with non-atopic subjects.

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There was a significant increase in sulfated glycosaminoglycan content in pathologic tendons compared to normal. The severity of depression symptoms following the start of dialysis treatment is an independent predictor of survival.

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Protein oxidation was likely due to the peroxides, as determined by FOX assay, released into the protein solution from the dressing. Here we discuss ethnic differences in genetic alterations and their impact on the susceptibility, progression, and treatment of prostate cancer.

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Daily documentation was once again shown not to enhance treatment effectiveness. The study sample consists of 4,712 men and 5,715 women aged 25 or older and free from heart disease in 1994/1995. The most compact domains were formed by the most hydrophobic polyelectrolyte, PSSS, while the most expansive domains were formed by the most hydrophilic polyelectrolyte, PGLU. For long-term outcomes, we excluded studies with fewer than 100 subjects and those without a control group.

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Findings can be used to inform the development of self-management interventions and to support health care professionals in recommending symptom self-management strategies to their patients. Evaluation of comparative cytochrome P450 2B4 model by photoaffinity labeling. Very high frequency of the His1069Gln mutation in Polish Wilson disease patients.

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Review finds combining angiotensin receptor blockers with ACE inhibitors in heart failure may only benefit people with contraindications to beta blockers. Using a case report form developed by the authors, a retrospective medical record review was performed of patients (0-18 years old) diagnosed with immediate-type FA between September 2014 and August 2015 in 14 tertiary hospitals in Korea. Reporter assay revealed that transcriptional activation of the CLDN8 promoter by androgen is dependent on these androgen-responsive elements. A hierarchical reentrant system explains the emergence of coherent visual objects from primitive features. All the subjects accomplished the standard questionnaire and ocular examinations.

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The objectives of this study are, first, to describe the incidence of primary liver cancer (PLC) and, second, to highlight its epidemiological characteristics from a geographical point of view. To date, no study has compared the diagnostic utility of color Doppler ultrasonography (CDUSG), Tc-99m (technetium-99m) pertechnetate uptake, and thyroid-stimulating hormone (TSH)-receptor antibody (TRAb) for the differential diagnosis of these two conditions. Our results demonstrated that miR-137 played an important role in regulating ketamine induced hippocampal neurodegeneration, possibly through CDC42. Molecular docking studies showed that fluoroquinolines has shown formation of hydrogen bond and good binding affinity with human Topo2a and Topo2b.

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Women with severe vulvar vestibulitis syndrome who do not respond to conservative management achieve good long-term well-being and decrease of dyspareunia by posterior vestibulectomy. Stearic fatty acid was significantly decreased after the fish diet. Detection of risk factors related to early death in these patients could be of aid for clinical and administrative decision making. Specific inhibitors of 5-lipoxygenase and 5-lipoxygenase-activating protein (FLAP) blocked airway mucus release and infiltration by eosinophils indicating a key role for leukotrienes in these features of allergic pulmonary inflammation.

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Costs can also be reduced by collaboration with prescribing providers to ensure that orders are written generically, and avoid unnecessary nursing visits. a total of 3mg/kg urethane was injected in 51 Balb-C mice aged 7-13 weeks of life. In conclusion, microarray analysis proved to be a valuable tool to identify a large number of genes and resulting pathways that may serve as novel drug targets or predict drug responsiveness for SJW or fluoxetine. Consecutive patients with acute cervical injuries at a single institution. Dopamine D(4) receptor (DRD4) gene variation has been associated with biased attention for contextually relevant information (e.g.

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Multicenter typing comparison of sporadic and outbreak Clostridium difficile isolates from geographically diverse hospitals. We have applied the so-called reciprocity theorem and developed an analytical model to compute the electric field and its spatial derivatives inside pseudocylindrical structures. This review provides an updated summary of the use of probiotics to improve sanitary conditions and enhance performance in broilers, demonstrating the role of probiotics as a reliable option to replace antimicrobial growth promoters. On energy, personality, and health: subjective vitality as a dynamic reflection of well-being. MIP-1a has chemotactic and pro-inflammatory properties, and is induced by YKL-40 in several lung disorders.

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A retrospective review was performed of all patients during a 1-year period with a long bone fracture treated in two urban pediatric Emergency Departments (EDs). We report a patient with a massive VAE that occurred in the semi-sitting position during a posterior approach to an extended cervical-thoracic level (C3-T2) intramedullary tumor, which interrupted the surgical procedure. From there an NO-dependent intermediate stimulus may reach the glomerular vasculature. It is an established antioxidant with an ability to ameliorate the UV-induced skin damage and chemically induced inflammation in lungs.

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Shorter CAG and GGN androgen receptor (AR) repeat polymorphisms are associated with stronger androgen signaling, and therefore, could influence lean mass and exercise performance during growth. Normal weight and optimal weight--description and evaluation of body mass Smoking, coronary artery disease and hypertension are related risk factors. Variations and defects in alternative splicing are well known to be associated with a variety of human diseases and the stress response. Because MVI can range from few to many invaded vessels, we evaluated the significance of MVI classification in this study.

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This review summarizes the functions of main T cell cosignaling axes and discusses their clinical application. The reluctance of resuscitation teams to appropriately challenge the incorrect order resulted in a high rate of inappropriate medication administration.

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The trace mineral concentrations of As, Cr, Cs, Sc, Th, and U in all of the samples were less than the defined tolerable upper intake level. Biogenetic hypothesis and first steps towards a biomimetic synthesis of haouamines. Although there were significant changes in the piritramide-binding proteins, alpha1-acid glycoprotein and albumin, during the postoperative acute phase response, the protein binding of piritramide did not change.

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Endothelium injury has been implicated in atherosclerosis, thrombosis, hypertension and other cardiovascular diseases. dsRNA-conditioned medium from HepaRG cells exerted a drastic antiviral effect in HCV replicons, and in the JFH-1-based HCV production cell culture system. Finally, we consider the interactions that occur between the two metals, reviewing the data that show how alterations in levels of one of the nutrients changes that of the other, and we examine the hypotheses explaining the interactions. The ultrastructure of megakaryocytes in polycythaemia vera and chronic granulocytic leukaemia. CARD11 is a multidomain adapter that is required for TCR signaling to the IkappaB kinase (IKK) complex.

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These data support the potential use of autologous AD-MSCs in the treatment of human cholestasis, and specifically of newborn biliary atresia, which could be beneficial for patients awaiting transplant. In addition, all these effects could be partially blocked by U0126, a specific inhibitor of mitogen-activated protein kinase kinase (MEK or MAPKK), or LY294002, a specific inhibitor of phosphatidylinositol 3-kinase (PI3K). Tx2: elevation of a full-thickness flap over the mesial root of P(2) and performing a notch at the height of the bone.

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A syndrome of multiple tics, myoclonic jerks, dystonia and vocal utterances. The detector was made up of units of a string, two plates, and two strain gauges. Prospects of in ovo feeding and nutrient supplementation for poultry: the science and commercial applications--a review.

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Nonetheless, they can be used as model compounds for studying the mechanisms of antimycobacterial action of thiosemicarbazones. Different target materials gave different measures for velocity resolution. Nutrients during the circulatory phase of digestion influence gastrointestinal motility and secretion. Electrophysiological evidence that systemic angiotensin influences rat area postrema neurons. In spite of the rejuvenating effect that autophagy is predicted to have on cells, our findings suggest that autophagy is not sufficient to extend lifespan.

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As the melatonergic pathways are dependent on the levels of serotonin availability as a necessary precursor, decreased melatonin is linked to depression and depression-associated disorders. fastidiosa diseases, and management of the problem is based solely in controlling the population of insect vectors, which is somewhat effective. We have optimized conditions for the chemiluminescent analysis of gene expression using high-density filter arrays (HDFAs). Automatically constructed mirror images can be a helpful tool for detecting asymmetries in faces. coli O157:H7 biofilm formation as well black magic design teranex review of related as suppress virulence-related genes.

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Out-of-hospital cardiac arrest patients resuscitated in an emergency department for at least 20 minutes, unless there was any return of spontaneous circulation (ROSC) within the time frame, were analyzed. SRs accounted for a small proportion of the articles and had low methodological scores. This is iva risek tablets done via a complementation test, which demonstrates whether or not a disruption of the cloned gene that is integrated into the genome can complement the original mutation. Foundations of planning of plastic operation of the upper lip in children with congenital complete bilateral cleft lip, alveolar process and palate The results suggested a high compatibility between the marshland strains of snail and both the hill and the marshland strains of parasite.

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Here, we tested the efficacy of whole-genome transcriptional profiling for identifying genes affecting starvation stress resistance. The products were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and acromicina sirve para la diarrhea causes transmission electron microscopy (TEM). Although culture and molecular laboratory studies can usually identify the precise etiologic agent in bacterial mycetoma, occasionally these methods fail to clarify this situation.

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PB-like structure formation was confirmed for both LG and LALF32-51 -E7 by TEM. In healthy individuals, small intestinal exposure to HCA resulted in a modest reduction in glycemia and stimulation of plasma GIP and glucagon, but no effect on plasma GLP-1 or insulin, or on glucose absorption. Fixation of the patellar limbs during MPFL aurex leather binder canada reconstruction may be optimized with the use of TS or BT over a PL technique. Upon arrival at the local hospital, she was unconscious and soon thereafter, developed respiratory arrest.

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Most youth with CP were aware of, and used, assistive technologies to enhance their computer access but were less knowledgeable nomyc 150 mg posologie metronidazole about accessibility options. In more distal parts of the rib they are located in the cranial half of 1 rib and the caudal half of the next cranial rib. The role of psychiatric consultation liaison nurses in ethical decisions to remove life-sustaining treatments. We conclude that LCDD may primarily affect the lung, present as a pulmonary cystic disorder, and lead to severe respiratory insufficiency.

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Direct approaches include using lectins labeled with 125I or conjugated to horseradish peroxidase or alkaline phosphatase, which can be detected by chromogenic or luminescent visualization systems. Maintenance of the structural macromolecule peptidoglycan (PG), which involves regulated cycles of PG synthesis and PG degradation, is clindamycin phosphate gel usp erytopia pivotal for cellular integrity and survival.

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In this work we use feedforward neural networks-a multilayer perceptron and its simplified variations-to equalize these signals. Assays to select revertants that were able to grow efficiently at a doneurin 10 mg hexal ag restrictive temperature failed, showing that these deletion mutants are genetically more stable than conventional substitution mutants. Chemoenzymatic synthesis, characterization, and application of glycopolymers carrying lactosamine repeats as entry inhibitors against influenza virus infection. Contractile responses to 5-carboxamidotryptamine, CGS 12066B, pindolol and propranolol were greater in SHRSP arteries than in WKY arteries, whereas contractions in response to 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT), alpha-methyl-5-HT and 2-methyl-5-HT did not differ between the two groups.

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These findings strongly suggest that the clarithromycin uses accumbens-ventral pallidal GABAergic circuitry is a substrate for the decrease in sensorimotor gating induced by mesolimbic DA overactivity. Inner Mitochondrial Membrane Disruption Links Apoptotic and Agonist-Initiated Phosphatidylserine Externalization in Platelets. Multiplex genotyping and allele frequency estimation in pooled DNAs using non-gel capillary electrophoresis. The aims of this study were to examine the effects of berberine, an alkaloid isolated from some medicinal herbs, on interleukin 8 (IL-8) and monocyte chemotactic protein 1 (MCP-1) expression in a human retinal pigment epithelial cell line (ARPE-19) stimulated with interleukin 1beta (IL-1beta) or tumor necrosis factor alpha (TNF-alpha).