Klaz is a semisynthetic 14-membered ring macrolide antibiotic. Klaz binds to the 50S ribosomal subunit and inhibits RNA-dependent protein synthesis in susceptible organisms. Klaz has been shown to eradicate gastric MALT (mucosa-associated lymphoid tissue) lymphomas, presumably due to the eradication of tumorigenic Helicobacter pylori infection. This agent also acts as a biological response modulator, possibly inhibiting angiogenesis and tumor growth through alterations in growth factor expression. (NCI04)
Other names for this medication:
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Bremon,
Clabel,
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