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Sendoxan (Cyclophosphamide)

Sendoxan is used alone or in combination with other medications to treat Hodgkin's lymphoma (Hodgkin's disease) and non-Hodgkin's lymphoma (types of cancer that begin in a type of white blood cells that normally fights infection); cutaneous T-cell lymphoma (CTCL, a group of cancers of the immune system that first appear as skin rashes); multiple myeloma (a type of cancer of the bone marrow); and certain types of leukemia (cancer of the white blood cells), including chronic lymphocytic leukemia (CLL), chronic myelogenous leukemia (CML), acute myeloid leukemia (AML, ANLL), and acute lymphoblastic leukemia (ALL). It is also used to treat retinoblastoma (cancer in the eye), neuroblastoma (a cancer that begins in nerve cells and occurs mainly in children), ovarian cancer (cancer that begins in the female reproductive organs where eggs are formed), and breast cancer. Sendoxan is also used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications or in children who experienced intolerable side effects with other medications. Sendoxan is in a class of medications called alkylating agents. When Sendoxan is used to treat cancer, it works by slowing or stopping the growth of cancer cells in your body. When Sendoxan is used to treat nephrotic syndrome, it works by suppressing your body's immune system.

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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In addition, differences in the associations by parity and ethnicity were explored. Patients with severe acute illness or disseminated CMV infection have high mortality. This effect of cadmium was weaker in cells made iron-deficient with the iron chelator, desferrioxamine, which was associated with repression of heme oxygenase-1 protein and mRNA expression. Interactions between the infectious-disease index and some sociodemographic variables were also associated with neurocognitive function.

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Identification of new donor variables associated with graft survival in a single-center liver transplant cohort. Genetic variants associated with angiotensin-converting enzyme inhibitor-associated angioedema.

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Whereas research on the antinociceptive effects of cigarette smoking has produced inconsistent findings, certain aspects of attentional processing repeatedly have been found to have an impact on pain perception. Our result demonstrated that the key components associated with the epilepsy symptoms had altered the regional function in the TLE patients, and the disruption of cortex-thalamus-striatum loop.

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We report on a 16-year-old adolescent male requiring staged bilateral hybrid hip arthroplasty within 3years of diagnosis of acute lymphoblastic leukaemia that ran a complicated course of multimodality treatment. Identifying Variations in Baseline Behavior of Killer Whales (Orcinus orca) to Contextualize Their Responses to Anthropogenic Noise. Local symptoms were defined as hematuria, voiding symptoms, urinary obstruction, and pelvic pain. We calculated attributable hospital days and years of life lost (YLL), based on the observed passive smoking and disease rates in Switzerland. We found substantial improvements in rod sensitivity in two participants: dark-adapted spectral sensitivity was rod-like after treatment and was cone-like before rods had recovered after a bleach.

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Estimates of dose to the translated heart were then made with the treatment planning system. The results presented here indicate that the programming effects of perinatal protein restriction are mediated by specific decreases in central leptin signalling to pathways involved in the regulation of food intake along with possible enhancement of different CNS leptin signalling pathways acting via the SNS to regulate bone mass and energy expenditure. Influence of vitamin C on salivary absorbed dose of 131I in thyroid cancer patients: a prospective, randomized, single-blind, controlled trial. The ambulation-increasing effects of MAP (1 mg/kg), CAF (10 mg/kg) and combination of MAP with CAF were almost equivalently inhibited by SCH 23390 (0.01 and 0.1 mg/kg SC) and YM-09151-2 (0.01 and 0.1 mg/kg SC).

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There is a growing need for sensors due to the development of prosthetic hands that have multiple degrees of freedom requiring finger coordination into different postures. Elevated cholesterol, low-density lipoprotein, triglycerides, and reduced high-density lipoprotein, were frequent in Vietnam veterans with chronic PTSD and are significant risk factors for coronary artery disease. Evidence supports the rationale for circadian rhythm regulation to prevent mood episode relapse in bipolar patients.

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Infectious and Noninfectious Pulmonary Complications in Patients With Primary Immunodeficiency Disorders. Embolization facilitates surgical removal when necessary, and this combination is the treatment of choice for scalp AVFs. We are witnessing the growing menace of both increasing cases of drug-sensitive and drug-resistant Mycobacterium tuberculosis strains and the challenge to produce the first new tuberculosis (TB) drug in well over 40 years. A new method is put forward for measuring the superhigh spectral resolution based on the Rayleigh criterion and the optical heterodyne, and the uncertainty of this method is analyzed.

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Carbon dynamics of mature and regrowth tropical forests derived from a pantropical database (TropForC-db). Correction: Early Loss of Splenic Tfh Cells in SIV-Infected Rhesus Macaques.

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Viewing this problem from the new angle allows us to derive a rich class of estimators, and obtain the classical dimension reduction techniques as special cases in this class. teeth are showed: supplementaries, conoides, tuberculates and infundibuliformes. Australian and New Zealand Clinical Trial Registry identifier: ACTRN12616000780459 . A case-control study of patient, medication, and care-related risk factors for inpatient falls.

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Androgen deficiency promotes differentiation into adipogenic lineage, and accumulation of adipocytes in the corpus cavernosum may contribute to erectile dysfunction. We present a convenient method to make an MRI-visible skull fiducial for 3D MRI-based stereotaxic procedures in larger experimental animals. Experimental methods for stimulation of bone healing by means of electrical energy. We studied the anti-inflammatory properties of probiotic strains and blueberry in a colitis model.

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Sensitization to self (virus) antigen by in situ expression of murine interferon-gamma. To determine the relationship between an FBL, type of treatment, and death in the management of NEC. Promoting advocacy and social responsibility is a requirement of medical education. Etiological investigation is fundamental, because most of time this condition is associated with more serious systemic complications which need specific care. Notably, complexation with HSA did not hinder the activity of silencing oligonucleotides inside cells, and the degradation of DNA strands in serum was significantly slowed.

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One study found no significant effects, and two studies reported no impact on depression. The rabbits were then killed, the heart and lungs were dissected and radiographed and the clots were harvested so that clot-to-blood radioactivity ratios could be determined. Effective treatment of experimental human endometrial cancers with targeted cytotoxic luteinizing hormone-releasing hormone analogues AN-152 and AN-207. A structural comparison revealed that a water-mediated hydrogen bond between one end of the inhibitor and a rigid portion of the protein surface in the shorter-chain inhibitor (E4P) complex is replaced by a direct hydrogen bond in the longer-chain inhibitor (6PGA) complex. The present findings support the development of TTM-grounded behavioral interventions targeted to obese patients.

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Following cardiac magnetic resonance imaging (MRI) showed a mass in the pericardium in the right atrioventricular groove with thrombotic material. For the detection of skeletal metastases with the 18F-NaF positron emission tomography/computed tomography study, the contribution of the positron emission tomography component was compared with the contribution of the computed tomography component. A digital-chip architecture for a 10(6)-synapse neural network is proposed.

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In boys with syndactyly, the authors advocate that parents be informed of this reconstructive option. Polymerase chain reaction assays were used for detection of viral pathogens.

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Research on older children and studies contrasting preschoolers with high versus low behavioral inhibition (BI) highlight several risk factors, but these have not been investigated in community samples of young children. By flow analysis of phosphorylated histone H3 or cell cycle distributions, insulin and X-10 were mitogenic at physiologically relevant concentrations (2 nm to 74 pm range), with X-10 being approximately 3-fold more mitogenic than insulin. Day-case elective laparoscopic cholecystectomy seems to be a safe and effective intervention in selected patients (with no or minimal systemic disease and within easy reach of the hospital) with symptomatic gallstones.

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Four of the probands and affected relatives had manifestations that further expanded the phenotype: gustatory lacrimation, hypospadias, imperforate anus, osteosclerosis, microcephaly, hypodontia, congenital vocal cord paresis, and congenital incomplete fixation of the transverse colon. The effects of altering intracellular and extracellular pH on uterine contractions were studied in guinea-pigs on day 7 (high progesterone) and day 15 (low progesterone) of the oestrous cycle. In these systems, the genes are represented by logical functions, and the controlling transcription factor protein molecules are real variables, which are produced and destroyed.

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A Computational Study (TDDFT and RICC2) of the Electronic Spectra of Pyranoanthocyanins in the Gas Phase and Solution. Visual recognition memory was examined in 310 normal adults (age range 18-91) and 60 patients with unilateral vascular lesions (30 right, 30 left) using the Continuous Visual Memory Test (CVMT). Based on the foregoing, we propose an action mechanism of soybean beta-amylase involving the interactions of three essential amino acid residues (Asp101, Glu186 and Glu380) in concert with Leu383, and assumed an indispensable role for Asp101. Video assessment is an emerging tool for understanding variation in surgical technique. The effect of miR-205 on TCF21 was determined by luciferase reporter assay and western blot.

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This investigation aims to understand the relevant optical concepts and to discuss the plausibility of this assertion. The level of the acid DNase activity in the hemocytes and digestive gland of the mussel Mytilus galloprovincialis after exposure to model marine pollutants, a detergent, gasoline and a copper salt, as well as to unknown environmental mixture at selected sampling sites, was investigated. The enhanced transmission effects have been related to the antidepressant effect of ECT, whereas the cholinergic effect has been attributed to its effects on memory and cognition as well as depression. This retrospective analysis of patients with classic KS confirms the efficacy and safety of PLD. Local-field calculation of the optical diamagnetic response of a metallic quantum well.

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Decreased vessel depictability might present difficulties at the clinical signal-to-noise ratio (SNR) level. Only few studies have been conducted so far with detailed population-related data on the incidence and relative risks of blindness, as well as the associated mortality. The primary outcome was the occurrence of a seizure within 7 days of TBI. Biological basis for the protective effect conferred by male circumcision against HIV infection.

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Cerebral hyperperfusion syndrome following a carotid endarterectomy This will set the foundation clinically for the best possible outcome. This study was conducted to determine whether Blastocystis species alters human intestinal epithelial permeability, to assess whether these abnormalities are rho kinase (ROCK)-dependent, and to investigate the therapeutic potential of the HMG-CoA reductase inhibitor Simvastatin in altered intestinal epithelial barrier function. However, recent proteomics and tissue-specific RT-PCR experiments revealed a small amount of H3t expression in somatic cells. Pituitary adenylate cyclase activating polypeptide is a potent calmodulin inhibitor.

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Drug utilisation in the nursing homes was high and many drugs were used chronically. Antinociceptive effects induced by intra-periaqueductal grey injection of the galanin receptor 1 agonist M617 in rats with morphine tolerance.

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Patients with persistent or recurrent EOC who had received one prior platinum-based chemotherapy regimen were eligible. We should be more vigilant for screening ethnic minorities as alarmingly high rates of hypovitaminosis D have been found in ethnic minorities living in Great Britain. We also investigated their neuropathic pain-alleviating effects in vivo using a rat spinal nerve ligation (SNL) model. NF-kappaB, but not p38 MAP kinase, is required for TNF-alpha-induced expression of cell adhesion molecules in endothelial cells.

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Type VII collagen DNA linkage analysis in a Japanese family with dominant dystrophic epidermolysis bullosa. Accordingly, different aspects of polysaccharide applications in cancer treatment or diagnosis were reviewed in this paper.

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Anti-leukotrienes--a new perspective in treatment of bronchial asthma. Importantly, it raises the critical question of defining other events that may drive a patient from a preclinical to a clinical phase of disease. A multinational, prospective, observational monitoring register.

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Diagnosis of acromesomelic dysplasia was based on radiographs of whole skeleton. At the ultrastructural level, a lot of nerve fibers clustered together in the prurigo nodularis dermal tissue. The formation of double strands containing up to four free base porphyrins is enabled without compromising duplex stability. Moreover, miR-376c-3p suppressed proliferation, viability, migration and invasion and induced G1/G0 arrest and cell apoptosis of SCC-25 cells.

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This relationship has resulted in a new field of science called osteoimmunology and provides a context for better understanding the pathogenesis of periodontal disease. Dietary recommendations for geriatric patients should take into account the needs of the patient and client preferences as well as economics. The patient was administered long-term immunosuppressive therapy and treated with the oral anti-viral medication, entecavir (ETV).

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We hypothesise that the heart-rate changes are due to central inhibition mediated by the vagus nerve during EEG suppression. The quantum-chemical calculation of an entire molecule of hagfish insulin was done by the ENFC method in which the matrix elements were calculated at the ab initio level using a minimal basis set with simulation of the aqueous solution environment. In addition, knocking-down the expression of 16 bHLH genes affected oogenesis and knock-down in the expression of 13 genes affected embryogenesis.

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Associations between cigarette smoking, pipe/cigar smoking, and smoking cessation, and haemostatic and inflammatory markers for cardiovascular disease. Up-regulated expression of desaturase genes of Mucor rouxii in response to low temperature associates with pre-existing cellular fatty acid constituents. Osteotomy was associated with an increased operative blood loss and length of surgery. 63, 2334-2340) was found to be deficient in N-acetylglucosaminyltransferase I.

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Fortunately, most of these injuries are neurapraxias that will recover spontaneously after conservative treatment. A possible relationship was detected between Helicobacter DNA and cholecystitis.

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Posttransplantation lymphoproliferative disorder in lung transplant recipients: a 15-year single institution experience. Role of lipids in the formation and maintenance of the cutaneous permeability barrier.

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Splitting the lineages based on genetic relationships and analysing the ENMs separately provided insights about the biogeographical processes that led to the current distribution of H. Complete remission in CD30-positive refractory extranodal NK/T-cell lymphoma with brentuximab vedotin. There is a high prevalence of right-to-left shunting pulmonary arteriovenous malformations (PAVMs), which are stroke risk factors, in hereditary hemorrhagic telangiectasia (HHT) patients.

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The omag online classes study was a prospective cohort study in a tertiary infertility center in Abu Dhabi, United Arab Emirates (UAE). Then, the rats were administered normal saline, sodium bicarbonate solution, or sucralfate suspension as an intervention by gastric lavage. Evidence of a steroidogenic enzyme gene dose effect on adrenal gene expression in hereditary rabbit congenital adrenal hyperplasia.

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The order parameters necessary to describe the above rotator phase transitions are identified. Adrenal and thyroid metachronous metastases from renal cell carcinoma. In this review we examine the relationship between breast and bowel cancer and suggest a possible explanation for the diverse points of view described in the literature. Interaction between histidine and Zn(II) metal ions over a wide pH as revealed by solid-state NMR spectroscopy and cyclophosphamide injection administration procedure DFT calculations. It appears that laparoscopy may play an important role in reviving the radical vaginal hysterectomy for patients with early cervical cancer.

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To review biochemical tests used in establishing the challenging diagnosis of adrenal insufficiency. Trends in use of treatment for adverse reaction to bactrim warfarin and direct oral anticoagulants in atrial fibrillation in Norway, 2010 to 2015. The results of our study showed the association between COX-1 high expression genotype (-842 AA) and COX-1 high expression allele -842A and risk of CP in infants with cystic periventricular leucomalacia (cPVL).

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The nutrients in the benthal sludge layers were increasing with time, and were concentrated at a layer 10 cm below the top surface. She was discharged home on rivaroxaban for prevention of thrombo-embolism. Thirty semistructured interviews were conducted with individuals at the state and local levels responsible for managing funds and deroxat 10 mg efficace significato implementing initiatives in selected disease areas across six states, using a standardized protocol through which select funds were followed from the state to the local level. The National Child Abuse and Neglect Data System reported that 3,140,000 abused or neglected children were reported in 1994 to child protective services agencies.

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In conclusion, DUSP6 has neuroprotective effects against glutamate-induced cytotoxicity in HT22 and pc-HNeu yeast infection pregnancy treatment diflucan and breastfeeding cells. These data provide evidence that a threshold of moderate MRI-LA as measured with a visual rating scale is associated with greater and/or equal impairment on tests of working memory versus episodic memory and provides a benchmark to assess the effect of MRI-LA on the clinical presentation of dementia. Acid exposure was analysed and compared by manual extraction of the data onto an excel spreadsheet. She had concurrently developed pneumonia and was admitted to the hospital.

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Heat-enhanced production of chitosanase from Streptomyces griseus in the presence of liposome. The purpose of this article is to provide an overview of the study design, rationale, and execution tamsulosin alternative drugs to accutane of this project as a model for health technology assessment based on comparative effectiveness of alternative clinical pathways. Changes in body weight influence bone mineral density, but the role of body composition is not clear in postmenopausal women. We quantitatively assessed the relative efficacy and safety of low-molecular-weight heparin vs standard heparin for the initial treatment of deep venous thrombosis. However, this analysis did show that the initial clinical signs and symptoms that are most frequently encountered are not very specific and can lead to a large differential diagnosis where AHT is often omitted.

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Previously, we reported that both methionine sulfoxide reductases MsrA and MsrB were able to reduce methionine sulfoxide residues in oxidized calmodulin. FTIR and fluorescence emission spectra of sulfonated PS and its ionomers Retrospective case study in which clinical data were posologia acyclovir comprimido 200 mg extracted from medical and pathological records.

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In patients with acute respiratory distress syndrome, controlled mechanical ventilation is generally used in the initial phase to ensure adequate alveolar ventilation, arterial oxygenation, and to reduce work of breathing without causing further damage to the lungs. Clinical reports suggest that large bone defects could be effectively restored by allograft bone transplantation, where allograft bone selection acts an important role. Therefore, the objective was to delineate injury causation scenarios for CRS-restrained children in side impacts and document probable contact points in the vehicle pantor 20 mg interior. Sodium fluorescein flow cytometry for the calculation of red cell volume is an exciting proposition in that the repeatability of the technique in a short time frame should allow for applications such as the measurement of surgical red cell volume loss.