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Spiroctan (Spironolactone)
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Spironolactone

Spiroctan comes as a tablet and suspension to take by mouth. It usually is taken once or twice a day. Take Spiroctan suspension consistently either with food or without food each time. Take Spiroctan at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Spiroctan exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Other names for this medication:
Spironolactone, Aldactone, Aldactazide, Aldactazine, Aldazida, Aldazide, Aldozone, Alexan, Alizar, Carpiaton, Espirone, Espironolactona, Expal, Kespirona, Lanx, Letonal, Osiren, Osyrol, Practon, Prilactone, Spiractin, Spiresis, Spirix, Spiroctan, Spirolang, Spirolon, Spiron, Spirono, Spironolacton, Spironolactona, Spironolakton, Spironolattone, Spirotone, Verospiron, Xenalon,

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Preliminary in vivo studies on the osteogenic potential of bone morphogenetic proteins delivered from an absorbable puttylike polymer matrix. Monthly levels of dry matter, ash, and crude protein were fairly stable except when there was new leaf growth, although year to year differences in dry matter were found inBrassaiopsis hainla (Bh),Dendrocalamus strictus (Ds),Ficus roxburghii (Fr), andQuercus semecarpifolia (Qs). Activation of the transcription factor, NF-kappaB, during hepatic ischemia/reperfusion injury is associated with proinflammatory mediator expression and is thought to be one of the initial triggers for the inflammatory response after reperfusion. As a reference sample for FRET, we used a fusion protein of a single donor and acceptor (ECFP-EYFP connected by a seven-amino acid linker) expressed in HeLa cells. Phocine distemper virus (PDV) seroprevalence as predictor for future outbreaks in harbour seals.

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We addressed this gap using a novel address-based sampling methodology to interview adolescents and parents who were affected by the 4th deadliest tornado outbreak in U.S. The primary cause of anemia in CKD patients is the reduction in the erythropoietin production, which results in a decrease of signaling molecule that stimulates red blood cell production. The first problem is its slow convergence rate if all the data have nearly the same value.

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Patients should be counseled on their increased risk prior to surgery. Etiopathologic factors predisposing to urate lithogenesis in Dalmatian and non-Dalmatian dogs represent diverse pathologic and/or physiologic processes involving purine nucleotide and ammonia synthesis, biodegradation, and excretion. The early but dissociative induction of VEGF between neuronal and pial cells suggests different roles of the protein in their cells after transient MCA occlusion.

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Twenty-one days of oral treatment (30 mg/kg) with the dual serotonin/noradrenaline reuptake inhibitor duloxetine or the triple serotonin/noradrenaline/dopamine reuptake inhibitor DOV 216,303 restored BDNF protein levels in the rat hippocampus, which were initially decreased due to injection stress. The application of reflective Nomarski differential interference contrast microscopy for the determination of quantitative sample topography data is presented. Ambient pH sensing in filamentous fungi: pitfalls in elucidating regulatory hierarchical signaling networks. The purpose of this review is to discuss technologic advances in ablative therapies with emphasis on the treatment of renal masses. It is necessary to detect NPM1 mutation and FLT3-ITD in newly diagnosed AML patients, especially in patients with high WBC and BPC, CD34-negative, normal karyotype, which might help to molecular classification and treatment.

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To study beliefs held by the general public in Iceland about medicines. SH-SY5Y cells were incubated with Epo at different time points and the nuclear and cytoplasmic levels of Nrf2 protein expression were examined by Western blotting and immunohistochemistry. Dysmenorrhea is a common gynecological complaint in adolescent and young females.

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A hyperglutamatergic state has been shown to play a possible role in the pathophysiology of autistic disorders. Elevated mRNA and enzyme activity levels of lysyl oxidase on day 7 in diabetic bone healing tissues also supports that the formation of a fibrotic matrix occurs in these tissues. Further, using an electron microscopic approach, we reveal the cellular and cytoarchitectural reorganization of the arcuate nucleus niche following exposure to contrasting seasons. The ultrastructure of chondrocytes in the cartilage of Sepia officinalis and Octopus vulgaris (Mollusca, Cephalopoda).

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Furthermore, we observed a significant difference in the bcl-2 gene expression between ischemia and drug groups. Transcutaneous multielectrode basket catheter for endocardial mapping and ablation of ventricular tachycardia in the pig. The bond strength was not influenced by the alloy, the luting material, or the etching treatment.

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HTA Implementation Roadmap in Central and Eastern European Countries. ABG II - cemented anatomic stems share their geometry and instrumentation with the uncemented version and provide a promising concept. The specific ratios of paired PAH isomeric compounds for source apportionment suggested that various pyrolytic procedures were the major origin in the Yellow Sea, whereas petrogenic cause only occurred at a small number of the monitoring sites. Articular cartilage degeneration in osteoarthritis (OA) involves type II collagen degradation and chondrocyte differentiation (hypertrophy). Hence, TLR ligands should be considered as adjuvants or immune modulators in SIT in human as to improve its efficiency regarding the Th1-Th2 balance of the immune response with a likely effect on therapy duration.

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Coordinated systems of community-based health care delivery: a vehicle for health care reform. Accurate diagnosis of a retained foreign body is crucial in anticipating and preventing complications, but diagnostic delay can occur. Treatment requires optimal therapy of the underlying left heart disease. PLEDs were also highly correlated with mortality, but not to the same degree as burst suppression and ASIDs.

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Analysis of Brca1-deficient mouse mammary glands reveals reciprocal regulation of Brca1 and c-kit. In the second operation, mask ventilation and tracheal intubation were easily conducted by using Berman pharyngeal airway. Recent reports identify critical roles for micro RNAs (miRNAs) on many developmental processes through regulation of gene expression. The favorable outcome of the present study highlights the role of speech therapy in such a case, where it often remains un-emphasized. Review of the major clinical trials involving statins reveals that LDL-C reduction is associated with a significant reduction in coronary events in men and women, older individuals, those with various other risk factors and those with either coronary artery disease or a high risk of developing it.

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Here, bromomethylcoumarins as reactive compounds for fluorescent labeling of RNA are developed as an attractive scaffold on which electronic properties can be modulated by varying the substituents. Nevertheless, co-expression of EGFRvIII and PTEN seem to be predictive factor of response to EGFR inhibitors currently tested in glioblastomas. Molecular determination of dermatophyte fungi using the arbitrarily primed polymerase chain reaction.

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In this Institutional Review Board-approved retrospective study, DCE-MRI of 84 women presenting 88 invasive carcinomas were evaluated by a radiologist and analyzed using quantitative computer-aided techniques. Despite the long-term efficacy of this therapy, a significant proportion of patients undergoing CTI ablation will develop atrial fibrillation (AF) during the follow-up and identifying them can have an important impact on their management. Autumnal territorial aggression is independent of plasma testosterone in mockingbirds. Electron microscopic imaging revealed the lack of tombusvirus-induced spherule-like structures in ESCRT-I or ESCRT-III deletion yeasts replicating TBSV RNA, demonstrating the requirement for these co-opted cellular factors in tombusvirus replicase formation. Magnesium fluctuations modulate RNA dynamics in the SAM-I riboswitch.

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For perfluorooctanoic acid recent fate-modeling studies have applied a pKa value of 2.8. Immediate chest wall reconstruction during pregnancy: surgical management after extended surgical resection due to primary sarcoma of the breast. RNAi-related mechanisms are implicated in the regulation of gene expression and repression of transposable elements in eukaryotes.

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In the real data example, there is no difference in AMI rates between treatments. We explored the possibility that one or several elements of the Ras/Raf MAPK cascade were involved. Patients who are at risk for poor self-care because of low levels of HF knowledge can be identified. To date, the pathogenic mechanisms underlying the initiation and progression of osteoporosis in HIV patients remain to be elucidated.

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Using ultrasound-guided mapping, all anticipated peripheral nerves were correctly identified via a direct approach from the skin incision. Adjuvant RT should be done as recommended before, to prevent recurrence, regardless of surgical resection and pathological diagnosis.

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Cortical synthesis of azimuth-sensitive single-unit responses with nonmonotonic level tuning: a thalamocortical comparison in the cat. Immunity to equine influenza: relationship of vaccine-induced antibody in young Thoroughbred racehorses to protection against field infection with influenza A/equine-2 viruses (H3N8). This specific activity is known in its averaged form as readiness potential (RP) and is considered to reflect the preparation of the voluntary movement. Thus, our findings suggested that let-7g inhibits OS cell malignant phenotype at least partly through targeting Aurora-B. An operational assessment should drive the strategic planning process.

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Acute exacerbations may be treated effectively with H2-receptor blockers and a variety of other agents. Haplotypes were constructed by genotyping nine single nucleotides polymorphisms (SNPs) throughout the COL7A1 gene.

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Balloon-expandable stent implantation in the SVGs of high risk patients is associated with a low early complication rate. Besides these effects the addition of the amphiphilic polymers stimulated growth of B. While most investigators in the field believe strongly that amyloid deposition is at the core of the disease, this writer finds that a more coherent, and thus more satisfying, schema can be based on the centrality of cytoskeletal abnormality. The accumulation of Glu is limited by a family of high-affinity Glu transporters.

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However, despite the clinical importance of these findings and the potential it provides as a model system for understanding targeted therapy, this approach has not yielded curative outcomes in most patients, and the biochemical pathways connecting c-KIT inhibition to cell death are not completely understood. The fibula free flap is the workhorse procedure for osseous reconstruction. In response to a question about the metaphors that they apply to teams, health professionals identified more nonsports than sports metaphors. The current research explores whether merely communicated beliefs affect evidence integration over time when it is not of interest to uphold the belief, and all evidence is readily available.

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Improvements in charge transfer were shown through electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV) and biphasic stimulation at clinically relevant levels. Spiral waves on excitable media strongly influence the functions of living systems in both a positive and negative way.

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One advantage is that the surgical cavity is not occluded with tissues, thus facilitating early identification of any recurrence. The aim of this study is to observe the efficacy of stereotactic radiotherapy (SRT) in lung cancer patients with brain metastasis and explore the nursing for those patients. We treated 22 young adults with fresh Galeazzi fracture-dislocation of the forearm, from January 2004 to January 2008, by percutaneous fixation of fracture by stacked elastic nailing at our institute.

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Moreover, the expression of an endogenous androgen receptor target gene is affected by the overexpression of the NCoA-1 or NCoA-3 PAS-B domains. Evaluation of the role of rats as reservoir hosts for fishborne zoonotic trematodes in two endemic northern Vietnam fish farms. Human head and neck cancer cells AMC-HN3 were treated with cisplatin- and ALA-mediated PDT individually, and also in combination.

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The development of the ruminal ulcer in the albino rats fed with low protein diet associated with rocking stress. A new convenient transformation of erythromycin A into clarithromycin.

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Psychosocial predictors of physical activity and health-related quality of life among adults with physical disabilities: an integrative framework. Thus, to better understand neurogenesis in human OE, we studied the expression of olfactory marker protein (OMP), TrkB and NeuroD in human nasal biopsies and autopsy specimens and compared these data with those obtained from normal and regenerating mouse OE. With experience and specialized techniques, total laparoscopic hysterectomy can replace abdominal hysterectomy for large uteri. In mammals, prolidase is particularly important in the catabolism of a proline-rich protein-collagen. To further investigate the role of maternal antibodies in the neonatal nervous system, we established a murine model to demonstrate that maternal IgG can access and persist in neonatal TG.

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With the advent of mass spectrometry based proteomics, the identification of thousands of proteins has become commonplace in biology nowadays. Electron microscopic localization of separated fractions after their renaturation The four measures also enabled the reconstruction of interaction parameters of simulated networks including the detection of time-dependent alterations.

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After having ruled out alternative interpretations, we can conclude that these results indicate that words and numbers are not only categorically organised at the semantic level but that they are also processed by different lexical mechanisms. We evaluated the hypothesis that plasma levels of adiponectin and leptin are independently but oppositely associated with coronary artery calcification (CAC), a measure of subclinical atherosclerosis. Using this assay, we compared transcriptional activation by three chimeric proteins containing the homeodomains of the mouse homeobox genes, Hoxa-5, Hoxb-6, and Hoxc-8. In addition, hevein-like peptides can exist in two forms, short and long. Quantitatively these novel fluctuation-induced phenomena are characterized by non-exponential time evolutions whose power law dependences can be determined analytically.

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This procedure was followed by a superficial temporal artery to superior cerebellar artery anastomosis for protection of the posterior circulation. Preoperative CCRT produced encouraging down-staging rates and was found to facilitate complete resection and sphincter saving in distal rectal cancer with acceptable toxicity.

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The distal branches of the external carotid artery anastomose with distal branches of the internal carotid artery provide important sources of collateral circulation to the brain. Why statistics matter: limited inter-rater agreement prevents using the psoriasis area and severity index as a unique determinant of therapeutic decision in psoriasis. The theoretical and applied ramifications of these findings are discussed.

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oleifera leaves (50 mg/kg body weight per day), sodium arsenite (10 mg/kg body weight per day) and sodium arsenite plus M. We observed that ditelluride in the concentrations of 1, 15 and 50 microM induced hyperphosphorylation of the high-salt Triton insoluble neurofilament subunits (NF-M and NF-L), glial fibrillary acidic protein (GFAP) and vimentin, without altering the immunocontent of these proteins. Metabolic acidosis treatment as part of a strategy to curb inflammation.

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edulis females collected from the region of sympatry were no more incompatible with M. Correlations among enthesitis, clinical, radiographic and quality of life parameters in patients with ankylosing spondylitis. This study deals with first experiences in clinical application of this new diagnostic technique. The six key role domains reaffirm the generic role of the nurse and the validation of the role clarifies and reinforces the centrality of the community nurse in the team.

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Both simulated and real data examples are presented to illustrate competitive performance of the new approach and compare it with several other existing methods. The combination of TUGr and TUGi may have added value in assessing cognitive impairment, which is a possible pre-stage of dementia. This study provided a novel insight into how abnormal protamination affects sperm head morphology as well as the relationship between sperm head morphology and its own molecular integrity.

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Fat embolism syndrome (FES) is a life-threatening condition in which multiorgan dysfunction manifests 48-72 hours after long bone or pelvis fractures. Histological examination showed abnormalities in the chondrocytes. We aim to evaluate the diagnostic value of intraoperative IC for surgical margin assessment during PN.

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These results suggest that MRP4 will be a useful prognostic marker for neuroblastoma and that clinical trials of irinotecan as a neuroblastoma treatment should monitor MRP4 expression. Severe ischemic injury does not necessarily determine the activation of humoral mechanisms of rejection mediated through DSA. Editorial Comment from Dr Cai to Predictive value of urinary interleukin-6 for symptomatic urinary tract infections in a nursing home population. aeruginosa form biofilm in the sinuses, which constitute an important bacterial reservoir for subsequent lung infection. Size exclusion chromatography further showed a partial dissociation of the complex in the presence of a specific DNA sequence.

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Imbalanced levels of parathyroid hormone (PTH), serum calcium (Ca) and phosphorous (P) are associated with an increased risk of cardiovascular (CV) death and fracture in dialysis patients with secondary hyperparathyroidism (SHPT). Increased competition does not lead to increased phylogenetic overdispersion in a native grassland. A rare and unusual case report of Langerhans cell histiocytosis.

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To identify the critical fragments that confer this protective immunity, mice were electroporated with plasmids encoding the TM domain associated with decreasing fragments of the EC domain and the antitumor protection afforded, the titer of antibody, and cytotoxic T lymphocyte (CTL) activity elicited to Neu protein were evaluated. Outcome measures included self-reported 24-hour quit attempts, seven-day point prevalence abstinence, progression along the stages of change, and mental health symptoms.

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This method may be used to assess the exact location of contacts between a protein and its cognate DNA and details of the complex structure. Secondly, it did not require phosphorylated ITAMs since it was unaffected by disruption of an ITAM-interaction motif in the SH2(C) domain of Syk or by simultaneous overexpression of the tandem SH2 domains.

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Complementary studies in the assessment of esophageal motility disorders. A new Middle Miocene tarsier from Thailand and the reconstruction of its orbital morphology using a geometric-morphometric method.

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The development of a 200-kHz air ultrasonic transducer that consists of a piezoceramic disc and metal housing, the latter acting as a radiating membrane, is discussed. Abdominal exploratory surgery will likely be necessary for diagnosis and treatment. Clinical features, polysomnography and outcome in patients with hypnic headache. However, interference between the SPR images of individual particles needs to be considered for high spatial resolution images and for strong scattering samples at certain incident angles of light.

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Lack of (or submaximal) prior mobilization in previously reported studies may have facilitated intracollection recruitment. This prospective study was designed to identify Mycobacterium sp growing on mycobacterial cultures contaminated with other microorganisms. Results were analyzed using proportional hazard models and controlled for age, sex, race, smoking status, current oral corticosteroid use, and severity of airway obstruction. Comparing (13)C NMR ciprofloxacin for bladder infection dosage chemical shifts for over 200 cyclohexanecarbonitriles reveals that equatorially oriented nitriles resonate 3.3 ppm downfield, on average, from their axial counterparts.

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Use of temozolomide in aggressive pituitary tumors: case report. How better josamycin vs clarithromycin collaboration among all ED services enhances staff safety and patient satisfaction.

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The newly synthesized TUMA could serve simultaneously as a co-monomer and co-initiator in the absence of commercial co-initiator. Significant correlations were found between the mean premenstrual betamox granules 250 mg severity and functional impairment. Prevalence of left atrial thrombus in patients with non-valvular atrial fibrillation.

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Observed trends in cancer site distributions could reflect screening practices, environmental and genetic factors, or a combination of these variables. We report a sensitive method for selective detection of target metabolites from the central metabolic pathway by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS), in which the MS signal is enhanced by up to three orders of magnitude in the course of in situ enzymatic amplification. Proteins present in nuclear or in mitochondrial extracts from normal or KSS-derived fibroblasts bound to a 280-bp mitochondrial DNA fragment encompassing a deletion breakpoint in the mitochondrial genome. Suppression of radiative losses of surface polaritons on nanostructured thin metal films. Laboratory adaptation occurred over time in side effects suhagra 50 mg both environments as reflected by a marked change in viability.

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The existence of these pyrimidinoceptors suggests that uridine nucleotides may play a role as intercellular efectin er 75 mg cena mediators, independently from adenine nucleotides. How PMA regulates TACE-dependent shedding and how TACE exhibits substrate specificity without proteolysis of other membrane proteins are questionable. A national epidemiological survey of oral mucosal lesions in Malaysia.

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Knitted collagen fabrics implanted in a rat abdominal repair model prevented herniation, pegasys interferon doses and connective tissue ingrowth was observed within the fabric by 12 weeks. Nowadays, there are approximately 8,000 rare diseases and it is estimated that 350 million people are affected by these conditions worldwide. Taken together, our analyses suggest that the human Nedd4L gene, especially the evolutionarily new isoform I, is a candidate gene for hypertension. Prevalence of naturally occurring surface antigen variants of hepatitis B virus in Korean patients infected chronically.

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Concomitant treatment with proton pump inhibitors in order to prevent gastrointestinal side effects is recommended by clinical guidelines. Murine bone marrow progenitor cells (BMPC, 1x10(6)) were exposed to various concentrations (0.1-50 fluzol side effects microM) of AZT in the presence and absence of zinc acetate (100 microM) or NAC (100 microM). Visualizing chromatographic separation of metal ions on a surface-enhanced Raman active medium. Our approach to this blind deconvolution approximation problem introduces a new robust interpolative 2-D GCD method based on a one-dimensional (1-D) Sylvester-type GCD algorithm.

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In this paper, the similarity measures, which both frameworks provide are used, so as the intestinal bacteria are detected and classified through uncertainty quantification in feature vectors. Circadian-clock control of protein synthesis and degradation in Gonyaulax polyedra. The effects were evaluated by immunoblotting assay revealed by enhanced chemiluminescence, with the aid of a specific antibody to the TRS protein. Moreover, vaccines are unable to eliminate virus from carrier animals. Echocardiographic rispen 3 mg pretty characterization of left ventricular apical hypoplasia accompanied by a patent ductus arteriosus.