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Many cell adhesion molecules have been discovered with a wide spectrum of responsibilities, including recruiting, activating, elongating, and maintaining. Mass spectrometry analysis of the co-purified proteins revealed multiple associated proteins, including core histones, which indicates that tagged histones may be incorporated to the nucleosome particle. Ska3 Phosphorylated by Cdk1 Binds Ndc80 and Recruits Ska to Kinetochores to Promote Mitotic Progression.

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In acute study, Aloe vera leaf (extract) powder in a dose-dependent manner significantly decreased duration of tonic hind limb extension in maximal electroshock seizure model, increased seizure threshold current in increasing current electroshock seizure model, and increased latency to onset and decreased duration of clonic convulsion in pentylenetetrazole (PTZ) model as compared with control group. Although there is ample evidence that dexamethasone (DEX) has an antiproliferative effect on C6 glioma cells, the molecular mechanism remains elusive. Three kinds of quinolones in liver tissues were higher than that in muscle tissues. In recent years, it has become evident that persons with immunodeficiency diseases, diabetics, transplant recipients, and prisoners are also particularly vulnerable. Eye flora of eight representative New Zealand White rabbits included four different species of Staphylococcus including S.

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Neuropsychological assessment included global cognitive, attention, and executive prefrontal functions, verbal fluencies, verbal memory, and visuospatial perception. This review focuses on the (vaso)relaxant capacity of ruthenium-based NO-donating and CO-donating molecules in view of their potential usefulness in the treatment of cardiovascular diseases and erectile dysfunction. An increased incidence of delayed cutaneous unresponsiveness was observed in each family.

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Medical students expressed expectations to work in large urban hospitals offering higher salaries. These results suggest that these exogenously added glycolipids could play a role as eutrophic, repairing and protective agents for the epidermis. K-wire and bone cement reconstruction is an effective and safe alternative method for large iliac bone defect repair when autologous rib graft is not available. Urologists are rarely criticized for performing too many investigations. Moreover, interactions between reactive oxygen and nitrogen species may alter the balance between pathways that yield nitrite and nitrate, without impacting the level of S-nitrosylation or extent of cell death.

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Evidence for the involvement of proline-rich tyrosine kinase 2 in tyrosine phosphorylation downstream of protein kinase A activation during human sperm capacitation. Imaging of the nerve in a search for drusen is often inconclusive, especially in children, where drusen may be buried below the surface of the nerve head. In support of this hypothesis, we found no difference in MAP kinase phosphorylation after an Ang II test injection in rats given prior treatment with repeated injections of vehicle, Ang II or Sar(1),Ile(4),Ile(8)-Ang II (SII), an Ang II analogue that activates MAP kinase without G protein coupling. Decreased prevalence and intensity of Loa loa infection in a community treated with ivermectin every three months for two years. All agonists induced dose-dependent changes in platelet counts due to accumulation of thrombi in the pulmonary vasculature.

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Slug down-regulation increased sensitivity to apoptosis induced by imatinib mesylate, etoposide, or doxorubicin. Threonine phosphorylation of the MMAC1/PTEN PDZ binding domain both inhibits and stimulates PDZ binding. Heart rate variability and dispersion of QT interval in patients with vulnerability to ventricular tachycardia and ventricular fibrillation after previous myocardial infarction.

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PIM1: a promising target in patients with triple-negative breast cancer. Data were collected (patient characteristics, diagnosis, antipsychotic treatment) and analysed at each audit. Temporal changes and the effect of subtherapeutic concentrations of antibiotics in the gut microbiota of swine. Superior optical properties of homogeneous liquid crystal alignment on a tin (IV) oxide surface sequentially modulated via ion beam irradiation. GABAergic neurons are widely represented in hindbrain nuclei controlling gastric motor functions, but limited information is available specifically about GABA(A)-responding neurons in brain visceral areas.

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The experimental group showed a significant improvement in quality of life after nurse-managed cognitive behavioural intervention. This means that the rigid tertiary structure of AFP is controlled by interaction with ligands, while their release results in transition of a protein molecule into a molten globule-like intermediate.

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These human disorders were linked to altered activities of vascular endothelial growth factor (VEGF) in the affected eyes. Right ventricular dysfunction and remodeling in chronic obstructive pulmonary disease without pulmonary hypertension. This is the first randomised study using a 3D navigation template to guide a unilateral lumbar pedicle screw with contralateral translaminar facet screw fixation. Integrin alpha1-null mice have delayed-onset progressive retinal degeneration associated with thickening of the basement membrane, dysmorphology of basal processes, synaptic malformations, and funduscopic abnormalities.

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Histopathologic classification of 171 cases of canine and feline non-Hodgkin lymphoma according to the WHO. Anisotropy of callosal motor fibers in combination with transcranial magnetic stimulation in the course of motor development.

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In heart transplant recipients, HHV-6 infection can cause hepatitis and pancreatic or upper digestive tract disorders. Peripheral vascular disease: carotid and vertebral brachytherapy for in-stent restenosis.

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Exploring the information needs of patients with cancer of the rectum. Lipid peroxidation and decline in antioxidant status as one of the toxicity measures of diazinon in the testis.

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In vitro efficacy of nitro- and halogeno-thiazolide/thiadiazolide derivatives against Sarcocystis neurona. The aim of this paper is to both qualitatively and quantitatively explore recruitment channels (eg, mass email, in-person referral, posted materials) and their success with enrollment into a Web-Assisted Tobacco Intervention study in this priority population of underserved and understudied smokers. Our high throughput, non-destructive technique for multiple analyte quantification in human liver specimens has potential for identification of biomarkers with prognostic and diagnostic significance.

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Effects of IL-1 receptor-associated kinase-4 gene silencing on human osteoblast-like cells. This study was undertaken to investigate the bioavailability of various L-carnitine esters (acetyl-L-carnitine and lauroyl-L-carnitine) and salts (L-carnitine L-tartrate, L-carnitine fumarate, L-carnitine magnesium citrate) relative to base of free L-carnitine. The probability of nonunion cement in severe collapsed bodies might be higher than that of union cement in mild collapsed ones, but was not statistically significant. Complexity in the genetic architecture of leukoaraiosis in hypertensive sibships from the GENOA Study.

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Development of a confocal optical system design for molecular imaging applications of biochip. The standard of care for detection and surveillance of bladder cancer consists of cytology and cystoscopy, but both examinations suffer from many limitations, including issues related to accuracy, invasiveness, and cost. Functional properties of some varieties of African yam bean (Sphenostylis stenocarpa) flour--III. We examined the associations between muscular strength, markers of overall and central adiposity, and cancer mortality in men.

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The results show a progressive degradation and resorption of both implant materials by means of a macrophagic reaction, which is at its most intense 1 month postimplant. The location of R bands, as well as the size and arrangement of constitutive heterochromatin blocks were determined. The presence of an abundant, latent matrix metalloproteinase (MMP) population which coexists with myocardial fibrillar collagen has been documented. Heterologous expression of the benzoate para-hydroxylase encoding gene (CYP53B1) from Rhodotorula minuta by Yarrowia lipolytica. IL-1 beta actively regulates functional ICAM-1 expression in vascular smooth muscle cells.

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In the standard Sensory Organization Test, both manipulation of sensory input (sway-referencing) and assessment of postural sway are based on ground reaction forces measured from a forceplate. bcr/abl fusion gene was detected by interphase FISH using dual-color bcr/abl probe in 6 cases.

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Problems of radiologic diagnosis of orbito-nasal communications. The objective of this literature review was to investigate the epidemiological basis in public health and clinical treatment for four psychotropic substance groups (i.e., alcohol, tobacco, illegal drugs, and pharmaceuticals) in Germany. A zebrafish model of tauopathy allows in vivo imaging of neuronal cell death and drug evaluation.

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Thrombomodulin is a membrane glycoprotein in the vascular endothelium. To reveal the mechanism underlying bidirectional modulation of cell invasion by TSG101, we used RNA interference to examine whether TSG101 depletion bidirectionally modulated matrix metalloproteinase (MMP)-9 expression in different cell types.

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This finding has important implications for clinical management and prognosis, and requires public preventive policies. Lymphocytes from CD-1 mice were cultured with each of the mycotoxins for 48 h to assess cytotoxicity. There is limited evidence suggesting that individuals from lower social classes are exposed to higher levels of environmental pollutants than are individuals from higher social classes. Approximation of Height of an Individual Using Somatometry of Human Male Skull. Multivariate statistics, different comparative and permutation tests and correlations were applied to compare the diatom assemblages, the Specific Polluosensitivity Index (IPS) and the diatom ecological guilds (low profile, high profile and motile) among the sites studied and to evaluate their responses to disturbances.

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Preoperative High Neutrophil-to-Lymphocyte Ratio Is Associated with High-grade Bladder Cancer. This paper describes a water pumping control system that is designed for production plants and implemented in an experimental setup in a laboratory. Mammary epithelial cell differentiation depends on lactogenic hormones, growth factors, and cell-cell and cell-substrate interactions, all of which modulate transcription factors essential for milk protein gene expression. Intestinal cell type targeted by S1P and early molecular survival pathways were researched using irradiated in vitro cell models and in vivo mouse models. It explores the perceived flow of knowledge between research, policy and practice, the perceived impeding factors, and suggested strategies for improvement.

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We compared the clinical and laboratory indices of 109 prospectively enrolled patients with meningitis (67 bacterial, 23 viral, 19 undefined etiology) and evaluated the validity of the CSF leukocyte aggregation test. The aim of this overview is the summary of contemporary knowledge in epidemiology, elementary pathophysiological implications and some possibilities of treatment of ischemic cardiomyopathy, which represents the most frequent cause of heart failure in developed countries. Differential neuroprotective properties of endogenous and exogenous erythropoietin in a mouse model of traumatic brain injury. A complete understanding of the state of nursing science in southern and eastern African countries will help nurses and midwives to understand gaps in clinical research knowledge, potentially direct their research to more critical topics, and inform funding bodies and policy-makers of the situation of nursing science in southern and eastern African countries.

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Survival and management of patients with irreversible intestinal failure has been made possible by the development of total parenteral nutrition (TPN). Ethical core considerations of prevention research of CVD on herbal medicine involve particular attention on the scientific validity of research, risk-benefit assessments, subject selection and vulnerability, and informed consent. Factors associated with adolescent overweight/obesity in Ho Chi Minh city. The effectiveness of long-term treatment of severe secondary hyperparathyroidism with intravenous calcitriol