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Topamax (Topiramate)

Topamax is an anticonvulsant medication used in the treatment of epilepsy and migraine headaches. Topamax is also commonly used off-label to treat a wide range of mood disorders, eating disorders, and to aid in substance abuse therapy. While Topamax's mechanism of action is unclear, we know that the drug blocks sodium channels in the body that deliver electrical impulses to excitable cells (such as nerve, muscle, and brain cells). By doing so, Topamax appears to enhance the activity of a chemical messenger (neurotransmitter) known as gamma-aminobutyric acid (GABA).

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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None of us have yet used this technique to treat iatrogenic filler induced blindness but we present the information for the benefit of patient safety, given the limited time the retina can survive vascular occlusion. The location of exudates causes morbidity when they are seen in optochiasmal region. Executive functioning accounted for additional variance in a broad range of daily living skills after controlling for IQ decline. Percutaneous Image-Guided Pancreatic Duct Drainage: Technique, Results and Expected Benefits. The corneal speckle obtained from OCT was modelled with the Generalised Gamma (GG) distribution that is characterised with a scale parameter and two shape parameters.

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We investigated in vitro mechanisms and the in vivo potential of pentoxifylline (PTX) to prevent this fibrogenic process. Furthermore, subtle structural differences in the two lutein binding pockets lead to substantial differences in the excited state properties of the two luteins. Systematic identification and treatment of smokers by hospital based cessation practitioners in a secondary care setting: cluster randomised controlled trial. Furthermore, the cells can adsorb nutrients (glucose) through the MOF shell but cease reproducing until the MOF casing is removed, at which point normal cellular activity is fully restored. Integration of negative experiences: A neuropsychological framework for human resilience.

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The modeling procedure includes characterization of the population being studied, identification in advance of dependent or outcome variables and independent or risk factors, specification of the modeling plan including univariate and multivariate analyses, evaluation of the model predictive performance, and the procedure for validation of the model. Acute dopamine depletion with branched chain amino acids decreases auditory top-down event-related potentials in healthy subjects.

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The summarisation of long-term, multi-site air quality/meteorological data from the Sydney basin on the SOM plane has identified a set of typical air pollution/meteorological spatial patterns in the region. Exposure to a nebulized, undiluted broth culture of MG for 10, 20, or 30 min produced uniformly severe lesions and serological responses. Our findings show that anthropogenic factors may profoundly impact the population genetics of a virus and its reservoir within the context of an emerging infectious disease. In the therapeutic study 8 females with stress incontinence, and 3 males and 5 females with urge incontinence were treated with magnetic stimulation twice a week for 5 weeks. The index patient was evaluated at an academic medical center, and DNA was obtained from the proband and both parents.

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These findings warrant a re-examination of the evolutionary forces underlying dosage compensation. The patient received postoperative synchronized chemotherapy but expired 8 months after admission. With proper control measures, DNA analysis should be considered reliable.

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Preparation, Structure, and Potent Antifouling Activity of Sclerotioramine Derivatives. Abdominal aortic aneurysm (AAA) treatment by means of stentgraft implementation is a less post-operationally after-effected, way of treating the AAA on the contrast to the more traditional method. To assess the effectiveness of traditional Chinese medicinal herbs for stopping bleeding from haemorrhoids and the adverse effects caused by these herbs. Methodological issues in biomonitoring of low level exposure to benzene. Intratumoral heterogeneity of HER2/neu expression and its consequences for the management of advanced breast cancer.

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Termination of absence status epilepticus by low-dose intravenous levetiracetam. The typical MR appearance of certain inflammatory joint disorders may be helpful in narrowing the wide differential diagnosis. ABS ( is a public database of known binding sites identified in promoters of orthologous vertebrate genes that have been manually curated from bibliography.

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Impact of a residency research program on research activity, faculty involvement, and institutional cost. Spray-dried chitosan as a direct compression tableting excipient. Endoscopic transcanal myringoplasty for tympanic perforations: An outpatient minimally invasive procedure. Duration of the surgical procedures are only marginally increased. Heterogeneous ultrastructure of melanosome formation in the goldfish induced by osmotic stress.

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The primary aim of the INTERGROWTH-21(st) Project is to construct new, prescriptive standards describing optimal fetal and preterm postnatal growth. The role of carbohydrate residues in CaMV antigenicity is evaluated. Dose errors introduced by metal artifacts were studied using phantoms with and without titanium inserts, and patient scans on which a metal artifact reduction method was applied. Besides, the results show energy and environmental benefits that clearly state the improvement of the products eco-profile, by reusing purified water use for irrigation, using the railway mode for the delivery of final products, when possible, and adopting efficient technologies, as the mechanical vapour recompression, in the pasteurisation and concentration of juice.

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Metabolic consequences of intermittent hypoxia: relevance to obstructive sleep apnea. Two independent mutations in SLC25A22 are associated with severe epileptic encephalopathy.

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Surface Hopping Excited-State Dynamics Study of the Photoisomerization of a Light-Driven Fluorene Molecular Rotary Motor. This allows us to formulate the hypothesis that the major driving force behind the price decline is a reduction of the intermediation margin (the difference between the retail and producer prices). In this study, magnetic molecularly imprinted polymer (MIP) was synthesized by using polydopamine. Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive haematological malignancy in the elderly, with a high frequency of cutaneous and bone marrow involvement and poor prognosis. Resection of liver metastases can prolong the long-term survival of the patients.

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Upon inhibition of ATM and Mcl-1 expression/activity using specific inhibitors of ATM and/or Mcl-1, we found significantly enhanced cisplatin-cytotoxicity and increased apoptosis of A549CisR cells after cisplatin treatment. The ligand efficiency was increased by including substituents that form stronger hydrophobic interactions with the P1 pocket. Decreasing the hyperexcitability of neurons through opening of voltage-gated potassium (Kv7) channels has been suggested as one of the protective mechanisms in the effective management of neuropathic pain.

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Menstrual status was determined by circulating estradiol (E2) and progesterone (P4) in ten junior elite female swimmers (15-17 yr). spinosa extract sharply reduced castor oil and magnesium sulphate induced diarrhea. The surrounding stroma was slightly edematous but without myxoid changes.

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Several lines of evidence indicate that the encoded protein is an oxido-reductase involved in the synthesis of capsanthin and capsorubin. Triplex-forming oligonucleotides (TFOs) linked to DNA damaging agents (e.g. maydis cell types vary most in the expression of genes related to metabolism. This peptide participates in kidney damage inducing fibrosis and epithelial mesenchymal transition (EMT). ATPase activity was assayed after cross-linking of the prototype NLS peptide with its pore receptor, or after preincubation of envelopes with NLS-albumin conjugates.

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Duration and severity of symptoms and levels of plasma interleukin-1 receptor antagonist, soluble tumor necrosis factor receptor, and adhesion molecules in patients with common cold treated with zinc acetate. Pitch plays a crucial role in speech and music, but is highly degraded for people with cochlear implants, leading to severe communication challenges in noisy environments. Neutropenia associated with quetiapine and sertraline: A case report and review of literature. However, a recent study suggested that a BRAF haplotype was associated with risk of sporadic melanoma in men. The gender aspect of drug use in adolescents, of comorbidity, prevention and therapeutic intervention is highlighted.

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We report on men treated with acupuncture for relief of vasomotor symptoms after castration therapy. PRL levels of patients were compared with 74 control subjects, separately for males and females. Three weeks after balloon injury, SMC-rich neointima with increased tissue factor (TF) activity developed in rabbit femoral arteries that were narrowed with a vascular occluder to disturb blood flow after stenosis.

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Retrospective chart review in the resident, attending, and adolescent medicine clinics during a 3-month period. A multimodal nonopioid anesthesia method avoids the necessity for intraoperative opioids, reduces the need for postoperative opioid use, and improves analgesia with less narcotic. Teaching home care electronic documentation skills to undergraduate nursing students. Monoclonal antibodies have been considered promising therapeutic entities due to their highly specific binding to antigens. Occlusive small vessel disease and subsequent lacunar infarcts and WML represent important PXE manifestations.

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This study examined resting metabolic rate (RMR) and thermic effect of a meal (TEM) among athletes who had participated in long-term anaerobic or aerobic exercise. Familiarity affects environmental sound processing outside the focus of attention: an event-related potential study. Further clarification of this relationship could inform more targeted, personalized interventions to prevent and/or alleviate mental illness in those with chronic medical conditions.

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These results suggest that Nano-Se can be used as an adjuvant drug to improve cancer cell sensitivity to the toxic effects of irradiation and thereby reduce damage to normal tissue nearby. Our study demonstrates the poor prognosis of SCLC patients with bone metastases. This meeting was supported by an unrestricted grant of the biotechnology company Genzyme, which did not have access to the meeting room or to the discussion sections.

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With the development of this questionnaire, the NDR becomes a clinical tool that contributes to further understanding the perspectives of adult individuals with diabetes. A proforma was designed and sent to all the surgeons treating CLP in India. In addition, SLP-76 through its association with FYB/FYN-T appears to play a role in IL-2 gene transcription following TCR activation. This curriculum was delivered to nursing faculty from throughout Kenya during a 5-day training course that incorporated presentations, case studies, exercises, and other teaching methods.

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Effect of low dose vitamin K2 (MK-4) supplementation on bio-indices in postmenopausal Japanese women. A DFT study on the magnetostructural property of ferromagnetic heteroverdazyl diradicals with phenylene coupler. Interpersonal psychotherapy: a model of intervention for borderline personality disorder Physical origin of hydrogen-adsorption-induced metallization of the SiC surface: n-type doping via formation of hydrogen bridge bond. The focus of this review is to explore the controversy between the broad acceptance of loop diuretics as a first-line treatment for heart failure (HF) and the data regarding their association to increased morbidity and mortality in HF.

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The EMG raw data and individual force-IEMG relations were influenced by the location of the electrode inserted into the muscle. The increasing prevalence of fatty liver disease requires routine assessment methods. Most plans engage in active managed care and have achieved at least some of their goals.

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We found that granular neurons of the olfactory bulb and dentate gyrus, vascular cells and ependymal cells throughout the brain, and peripheral sensory neurons expressed tdtomato in response to TAM treatment. In general, the major clinical features that were relevant to the presenting problem were adequately documented, although fever was not mentioned as a presenting complaint in one quarter of the cases. Subsequently, placebo or citalopram 20 mg were administered i.v. Reimbursements were derived from the average of insurance carriers.

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Evidence for interaction between markers in GABA(A) receptor subunit genes in an Argentinean autism spectrum disorder population. Here we report the synthesis and reactivity of LiO2 in liquid NH3 at cryogenic temperatures and conclude that LiO2 is the most reactive oxygen species in Li-O2 batteries. In predentine, labelling was more dense at the transition zone between the inner proximal third and the two outer thirds.

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2-Aryl benzimidazoles: human SCD1-specific stearoyl coenzyme-A desaturase inhibitors. A wide range of neoplasms, both primary and metastatic, occur in the mediastinum, which pose considerable diagnostic difficulties. miRNA array analysis of two types of breast cancer cells showed that miR-200c expression was inhibited in mesenchymal TNBC cells, but increased after TAM treatment due to demethylation of miR-200c promoters. On the registration of time and the patterning of speech movements.

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Fundamental trade-offs between information flow in single cells and cellular populations. No significant difference was observed in fecal excretion of cholesterol plus coprostanol and hepatic cholesterol concentration between unesterified plant sterols and plant sterol oleates. In a second phase, each status is refined using a numeric estimation of the proximity between a scenario and a session.

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Current methods for analysis of spectroscopic optical coherence tomography (SOCT) signals suffer from an inherent tradeoff between time (depth) and frequency (wavelength) resolution. IVIg dose increase in multifocal motor neuropathy: a prospective six month follow-up. We performed posterior leaflet extension with a patch of bovine pericardium. To determine its long-term effects, we established C3H10T1/2 cells expressing Nanog constitutively. The aim of this study was to define the impact of the presence of axillary nodal metastases on lymphatic mapping and sentinel lymph node (SLN) identification rate in patients with early breast cancer.

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Here, we introduce candidate stem and progenitor cells suitable for SUI treatment, show how the functional homogeneity and state of maturity of differentiated cells crucial for proper tissue integration can be assessed electrophysiologically prior to their clinical application, and discuss the trophic potential of adult mesenchymal stromal (or stem) cells in regeneration of neuronal function. Study of the toxicity of pentaerythritol di-(p-methylbenzeneboronate).

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On the basis of its unique local and extended structure, the ORR specific activity of Ni-Pt 2D nanoframes (5.8 mA cmPt-2) was an order of magnitude higher than Pt/carbon. Using the rate of growth of the accompanying induced linear dichroism following application of an applied electric field, the dynamics of carbon nanotube alignment is studied in suspensions of octadecylamine functionalised single walled carbon nanotubes, ODA-SWCNTs, in 1,2 dichloroethane. We evaluated the effects of three-dimensional imaging on surgical performance and its influence on surgeons at different experience levels in a prospective randomized trial. A polymorphic portion of the inactivated X-linked gene was amplified after selective digestion of the active X-chromosome with a methylation-sensitive restriction enzyme, Hpa II.

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Optimal treatment is selected based on polysomnographic findings and symptoms, and applied based on the underlying pathophysiologic components. Statistical analysis revealed that index injury occurrence was associated with higher levels of anterior pelvic tilting and thoracic side bending throughout the airborne (swing) phases of sprinting, whereas no kinematic differences during running were found when comparing players with a recent hamstring injury history with their matched controls. Follow-up laparoscopy is often indicated because of the association with secondary adhesive formation.

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Forty one practicing psychiatrists used a clinical interview to evaluate the current treatment status, acceptance of current medication, and current life satisfaction. In maize, profilins exist as a multigene family containing 4 or more members which are highly similar to each other but substantially less similar to profilins from animals and lower eukaryotes. Fos-ir neurons showed strong ipsilateral occurrence in the medial preoptic, ventrolateral part of the ventromedial, and ventral premammillary nuclei, sexually dimorphic regions involved in reproductive endocrine regulation. The autoantibodies EMA and anti-tTG were evaluated in supernatants of cultured sigmoid and duodenal biopsies from patients on a gluten-containing diet.

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Low energy effects of new interactions in the electroweak boson sector. Cell apoptosis and expression of hypoxia-inducible transcription factor-1 alpha in kidney tissue after severe burn with delayed fluid resuscitation in rats in areas of different altitude

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We describe the case of a giant LV pseudoaneurysm as a late complication of multiple epicardial and endocardial VT ablations in a female in her 50s with known cardiac sarcoidosis. Although three patients developed transient cerebrospinal fluid leaks with symptoms of meningitis, no permanent neurological morbidity resulted from the use of the approach. The ulnar forearm flap is favoured due to the less hairy skin of the ulnar forearm region and the more conveniently located donor area. The catalytic performances of supported gold nanoparticles depend critically on the nature of support. Small bowel and colorectal muscle biopsy sampling requires a surgical approach.

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It has been previously shown that lesions of the dorsal striatum can disrupt performance on a variety of cognitive tasks related to prefrontal cortex function. Based on our findings, head ATs or other organizational leaders may consider using personality assessments during interview processes, or athletic training program directors may be able to better guide students interested in athletic training based on knowledge of their personalities. Excimer laser to open refractory subclavian occlusion in 12 consecutive patients.

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For the last years, thiazole derivatives have focused too much attention to develop different new CNS active agents. It is postulated that the human stomach is the natural reservoir and that spread occurs by oral-oral or fecal-oral transmission. Toxicity was scored according to the National Cancer Institute CTCAE (Common Terminology Criteria for Adverse Events) v4.03. The use of traditional neuroleptics in children and adolescents.

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We discuss the methodology of diagnostic research and underscore the relevance of decision analysis in the process of evaluation of diagnostic tests. Following selection with meropenem (MEM) at a subinhibitory concentration, two morphologically different mutants, designated 37662RM1 and 37662RM2, were obtained and characterised. The method consists of etambutol tabletas 400 mg shotgun polymerization of three truncated monomeric gene units using a specific linker, followed by cloning of the recombinant clones and screening them for the presence of concatemeric genes of defined length. The mean visual acuity at first presentation and the duration of follow-up was the same as in the treatment group. Dual-linker gold nanoparticles as adjuvanting carriers for multivalent display of recombinant influenza hemagglutinin trimers and flagellin improve the immunological responses in vivo and in vitro.

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Naturally occurring protease inhibitors potent against the human immunodeficiency virus. The lymphocyte/platelet binding assay is a simple, reproducible, specific and cost efficient assay for measurement of PIF. However, ultimately, amorion comp 875 mg/125 mg hintavertailu the most cost-effective HPV vaccine will be determined by their relative price. A clinical trial of low dose methotrexate therapy in patients with rheumatoid arthritis Interactions of alkali metal chlorides with phosphatidylcholine vesicles.

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We identify scenarios in which direct coupling of electric fields to peripheral nerve could be a determining factor for electric field limits. Bounds on the polymer-length distribution in equilibrium polymerization. The reliability of linear position transducer and force plate measurement of explosive force-time variables during a loaded jump squat precio flutamida 250 mg in elite athletes.

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Cyclosporin A (CyA) has been reported to be an effective treatment of adult polymyositis (PM) and dermatomyositis (DM) refractory to corticosteroid therapy. Cortical perfusion measured with ASL correlated with prosteride centurion laboratories india microspheres and reliably detected changes in renal perfusion in response to physiologic challenge. To investigate missed appointments in a South African tertiary hospital. Moreover, using human carotid artery endarterectomy specimens, P947 facilitated discrimination between histologically defined MMP-rich and MMP-poor plaques.

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In this paper, we develop a conceptual framework to assess the probability that insurers will use SI for favourable risk-selection in BI. Health-related quality of life (HRQOL) is a person-centered concept. We describe a model CBO placement program within a family medicine residency in Harlem, New York City. The objective of this study was to evaluate the practicability of a prospective study of FMH fluconazole 100 mg capsulas precious moments in the general population based on antepartum maternal blood testing and neonatal anemia.

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Forceps and vacuum injuries to the cornea: histopathologic features of twelve cases and review of the literature. To elucidate the contributions of SmpB and tmRNA to RNase R recruitment, we evaluated Escherichia coli-Francisella tularensis chimeric variants of tmRNA and SmpB. A class of approaches, based on the guilty knowledge technique (GKT), assume that metronidazole 500mg tablets pregnancy symptoms guilty individuals will recognize specific crime-relevant details, whereas innocent individuals will not.

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Elucidation of the pathways downstream of Ex-NMDARs in HD could help provide novel therapeutic targets for this disease. Association of prenatal exposure to benzodiazepines and child internalizing problems: A sibling-controlled cohort study. All but 4-hydroxycinnamic acid were ectiban 10 mg precious moments stimulatory at the doses tested. In plants, embryogenesis generally occurs through the sexual process of double fertilization, which involves a haploid sperm cell fusing with a haploid egg cell to ultimately give rise to a diploid embryo. Peritoneal biopsies showed a continuous flat mesothelial cell layer in non-EOC patients, whereas in advanced EOC, the mesothelium was a discontinuous layer of rounded cells.

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More research is also needed on the immunology and diagnosis of the disease and the factors involved in the resistance of young animals. Although many studies have focused on the evolution of social characteristics in ants, bactrim antibiotics for sinus infection little is known about the evolution of worker morphology at a macroevolutionary scale.

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Some consequences when the assumptions for the analysis cefzon side effects of variance are not satisfied. Current status of diuretics, beta-blockers, alpha-blockers, and alpha-beta-blockers in the treatment of hypertension.

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Laparoscopic Hyperthermic Intraperitoneal Perfusion Chemotherapy for Patients with Malignant Ascites Secondary to Unresectable Gastric Cancer. In the majority of clear cell RCC (ccRCC), the most frequent and highly vascularized RCC subtype, HIF is constitutively activated by inactivation of the von Hippel-Lindau gene. A MEDLINE database search (via the PubMed interface) and an EMBASE database search (via the Dialog interface) of the past 35 years was performed. miR-26a/b could suppress tumor tumorigenesis and angiogenesis by targeting the sensaval depression quiz HGF-VEGF axis and could serve as a potential treatment modality for targeted therapy in the clinical treatment of gastric cancer.